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Query: NC_012659:1008028:1011713 Bacillus anthracis str. A0248, complete genome

Start: 1011713, End: 1011853, Length: 141

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017200:1157835:116377411637741163974201Bacillus thuringiensis serovar finitimus YBT-020 chromosome,signal peptidase I8e-1992.4
NC_005957:1037205:103816110381611038361201Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein8e-1992.4
NC_007530:1007140:101175310117531011953201Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein8e-1992.4
NC_003997:1007139:101175210117521011952201Bacillus anthracis str. Ames, complete genomehypothetical protein8e-1992.4
NC_006274:1040836:104344210434421043642201Bacillus cereus E33L, complete genomehypothetical protein8e-1992.4
NC_005945:1008000:101164710116471011847201Bacillus anthracis str. Sterne, complete genomehypothetical protein8e-1992.4
NC_011969:1084000:108501310850131085213201Bacillus cereus Q1 chromosome, complete genomehypothetical protein8e-1992.4
NC_016779:991298:992817992817993017201Bacillus cereus F837/76 chromosome, complete genomehypothetical protein8e-1992.4
NC_011773:1050000:105401610540161054156141Bacillus cereus AH820 chromosome, complete genomehypothetical protein2e-1891.3
NC_010184:1017000:101816710181671018367201Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein2e-1787.8
NC_004722:1008500:100954710095471009747201Bacillus cereus ATCC 14579, complete genomehypothetical protein2e-1787.8
NC_011725:1032500:103359010335901033790201Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-1787.8
NC_017208:1050414:105140410514041051544141Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein3e-1787
NC_014171:1018338:101935210193521019492141Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein3e-1787
NC_011772:1011220:101223110122311012371141Bacillus cereus G9842, complete genomehypothetical protein3e-1787