Pre_GI: BLASTN Hits

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Query: NC_012563:2566500 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2566500, End: 2584374, Length: 17875

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_012563:21014492101449212008818640Clostridium botulinum A2 str. Kyoto, complete genome0686BLASTN svgBLASTP svg
NC_012563:17043451704345173190427560Clostridium botulinum A2 str. Kyoto, complete genome2e-166593BLASTN svgBLASTP svg
NC_012563:29254722925472296409938628Clostridium botulinum A2 str. Kyoto, complete genome3e-147529BLASTN svgBLASTP svg
NC_010674:28176512817651283776520115Clostridium botulinum B str. Eklund 17B, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_010516:23051102305110232828423175Clostridium botulinum B1 str. Okra, complete genome7e-136492BLASTN svgBLASTP svg