Pre_GI: BLASTN Hits

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Query: NC_012563:2203037 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2203037, End: 2224765, Length: 21729

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_014330:16986216986219337123510Brachyspira pilosicoli 95/1000 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_019908:46328146328148754024260Brachyspira pilosicoli P43/6/78 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_018604:12928891292889131203019142Brachyspira pilosicoli WesB complete genome2e-1385.7BLASTN svgBLASTP svg
NC_018604:838932*83893286441725486Brachyspira pilosicoli WesB complete genome2e-0765.9BLASTN svgBLASTP svg
NC_010520:21715842171584219449022907Clostridium botulinum A3 str. Loch Maree, complete genome08381BLASTN svgBLASTP svg
NC_010674:61596361596363966223700Clostridium botulinum B str. Eklund 17B, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010516:20640272064027208498120955Clostridium botulinum B1 str. Okra, complete genome09121BLASTN svgBLASTP svg
NC_010723:57525457525460199426741Clostridium botulinum E3 str. Alaska E43, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010723:29895429895431770918756Clostridium botulinum E3 str. Alaska E43, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014328:26435882643588266721023623Clostridium ljungdahlii ATCC 49587 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_008593:21367592136759215512718369Clostridium novyi NT, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_003366:2057656*2057656208209924444Clostridium perfringens str. 13, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_020291:74432974432976571421386Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome7e-1073.8BLASTN svgBLASTP svg
NC_003869:1643682*1643682167230228621Thermoanaerobacter tengcongensis MB4, complete genome6e-0763.9BLASTN svgBLASTP svg