Pre_GI: BLASTN Hits

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Query: NC_012473:46000 Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequence

Start: 46000, End: 85004, Length: 39005

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_014331:57769*577699580738039Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete012850BLASTN svgBLASTP svg
NC_007322:57710577109516337454Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, complete07388BLASTN svgBLASTP svg
NC_005707:12735127353784225108Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence02906BLASTN svgBLASTP svg
NC_014331:112209922099Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete5e-83317BLASTN svgBLASTP svg
NC_007322:112209922099Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, complete5e-83317BLASTN svgBLASTP svg