Pre_GI: BLASTN Hits

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Query: NC_011896:1096500 Mycobacterium leprae Br4923, complete genome

Start: 1096500, End: 1115212, Length: 18713

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008595:11766581176658119686720210Mycobacterium avium 104, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_008595:22528302252830227372020891Mycobacterium avium 104, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_011896:36344836344838894925502Mycobacterium leprae Br4923, complete genome04758BLASTN svgBLASTP svg
NC_011896:56364156364158345319813Mycobacterium leprae Br4923, complete genome01245BLASTN svgBLASTP svg
NC_011896:34746*347465709922354Mycobacterium leprae Br4923, complete genome01241BLASTN svgBLASTP svg
NC_011896:26609692660969268009919131Mycobacterium leprae Br4923, complete genome01150BLASTN svgBLASTP svg
NC_002677:10965001096500111516918670Mycobacterium leprae TN, complete genome034390BLASTN svgBLASTP svg
NC_002677:36343236343238893225501Mycobacterium leprae TN, complete genome04758BLASTN svgBLASTP svg
NC_002677:26428602642860268248339624Mycobacterium leprae TN, complete genome01251BLASTN svgBLASTP svg
NC_002677:56350056350058344419945Mycobacterium leprae TN, complete genome01245BLASTN svgBLASTP svg
NC_002677:34750*347505709922350Mycobacterium leprae TN, complete genome01241BLASTN svgBLASTP svg