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Query: NC_010673:82586:100358 Borrelia hermsii DAH, complete genome

Start: 100358, End: 100954, Length: 597

Host Lineage: Borrelia hermsii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008710:79100:100282100282100872591Borrelia turicatae 91E135, complete genomephosphoribosyltransferase5e-106383
NC_011244:94756:112474112474113064591Borrelia recurrentis A1, complete genomehypothetical protein1e-100365
NC_002967:1589069:158847015884701589072603Treponema denticola ATCC 35405, complete genomephosphoribosyl transferase domain protein4e-43174
NC_008228:2068641:206864120686412069198558Pseudoalteromonas atlantica T6c, complete genomeputative hypoxanthine phosphoribosyltransferase7e-1787
NC_008698:560529:576595576595577365771Thermofilum pendens Hrk 5, complete genomephosphoribosyltransferase2e-0652