Pre_GI: BLASTP Hits

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Query: NC_009882:167350:177150 Rickettsia rickettsii str. 'Sheila Smith', complete genome

Start: 177150, End: 177350, Length: 201

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from from a patient with Rocky Mountain spotted fever. Causative agent for Rocky Mountain Spotted Fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia rickettsii was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009488:186000:204960204960205169210Orientia tsutsugamushi str. Boryong, complete genomepreprotein translocase subunit SecE5e-0649.7
NC_010793:1811401:183095618309561831156201Orientia tsutsugamushi str. Ikeda, complete genomepreprotein translocase SecE subunit4e-0650.1
NC_012633:169444:175628175628175828201Rickettsia africae ESF-5, complete genomePreprotein translocase SecE subunit7e-2199
NC_009881:166500:181572181572181778207Rickettsia akari str. Hartford, complete genomepreprotein translocase subunit SecE3e-1890.5
NC_017058:1255623:127492912749291275129201Rickettsia australis str. Cutlack chromosome, complete genomepreprotein translocase subunit SecE8e-2095.9
NC_009883:277409:287764287764287964201Rickettsia bellii OSU 85-389, complete genomepreprotein translocase subunit SecE1e-1891.7
NC_007940:1235250:125433012543301254530201Rickettsia bellii RML369-C, complete genomePreprotein translocase SecE subunit1e-1891.7
NC_016929:141972:156782156782156982201Rickettsia canadensis str. CA410 chromosome, complete genomepreprotein translocase subunit SecE2e-2097.4
NC_009879:141000:155746155746156009264Rickettsia canadensis str. McKiel, complete genomepreprotein translocase subunit SecE4e-2096.7
NC_003103:164972:174758174758175012255Rickettsia conorii str. Malish 7, complete genometranslocase1e-2098.2
NC_007109:1206421:122685812268581227154297Rickettsia felis URRWXCal2, complete genometranslocase1e-2098.6
NC_015866:173951:180068180068180322255Rickettsia heilongjiangensis 054 chromosome, complete genomepreprotein translocase subunit SecE2e-2098.2
NC_016931:171444:177572177572177772201Rickettsia massiliae str. AZT80 chromosome, complete genomepreprotein translocase subunit SecE7e-2199
NC_016930:165376:175189175189175389201Rickettsia philipii str. 364D chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_017056:141500:156559156559156759201Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomepreprotein translocase subunit SecE4e-1890.1
NC_017049:140000:154750154750154950201Rickettsia prowazekii str. Chernikova chromosome, complete genomepreprotein translocase subunit SecE4e-1890.1
NC_017051:140000:154754154754154954201Rickettsia prowazekii str. Dachau chromosome, complete genomepreprotein translocase subunit SecE4e-1890.1
NC_017048:484000:498715498715498915201Rickettsia prowazekii str. GvV257 chromosome, complete genomepreprotein translocase subunit SecE4e-1890.1
NC_017050:141500:156549156549156749201Rickettsia prowazekii str. Katsinyian chromosome, complete genomepreprotein translocase subunit SecE4e-1890.1
NC_000963:141500:156550156550156750201Rickettsia prowazekii str. Madrid E, complete genometranslocase4e-1890.1
NC_017057:142000:156771156771156971201Rickettsia prowazekii str. RpGvF24 chromosome, complete genomepreprotein translocase subunit SecE4e-1890.1
NC_017042:251515:257655257655257855201Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, completepreprotein translocase subunit SecE7e-2199
NC_016909:171018:177198177198177398201Rickettsia rickettsii str. Arizona chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_016913:974212:991666991666991866201Rickettsia rickettsii str. Brazil chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_016908:167423:177223177223177423201Rickettsia rickettsii str. Colombia chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_016911:167398:177191177191177391201Rickettsia rickettsii str. Hauke chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_016914:167537:177330177330177530201Rickettsia rickettsii str. Hino chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_016915:162841:177421177421177621201Rickettsia rickettsii str. Hlp#2 chromosome, complete genomepreprotein translocase subunit SecE7e-2199.4
NC_010263:167450:177243177243177443201Rickettsia rickettsii str. Iowa, complete genomeprotein translocase subunit7e-2199.4
NC_016639:175846:178313178313178567255Rickettsia slovaca 13-B chromosome, complete genomePreprotein translocase SecE subunit1e-2098.2
NC_017065:175856:178377178377178577201Rickettsia slovaca str. D-CWPP chromosome, complete genomepreprotein translocase subunit SecE7e-2199
NC_017062:141270:157550157550157750201Rickettsia typhi str. B9991CWPP chromosome, complete genomepreprotein translocase subunit SecE2e-1890.9
NC_017066:140853:157133157133157333201Rickettsia typhi str. TH1527 chromosome, complete genomepreprotein translocase subunit SecE2e-1890.9
NC_006142:140853:157133157133157333201Rickettsia typhi str. Wilmington, complete genometranslocase2e-1890.9