Pre_GI: BLASTN Hits

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Query: NC_009697:419443 Clostridium botulinum A str. ATCC 19397 chromosome, complete

Start: 419443, End: 437866, Length: 18424

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A ATCC 19397 (NCTC 4587, NCTC 7272) is a stock, type A toxin-producing, laboratory strain of known toxicity. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008710:621822*62182266159939778Borrelia turicatae 91E135, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_012225:21272721272723571322987Brachyspira hyodysenteriae WA1, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_012563:4004709*4004709403727332565Clostridium botulinum A2 str. Kyoto, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_012563:519037*51903754582126785Clostridium botulinum A2 str. Kyoto, complete genome2e-102381BLASTN svgBLASTP svg
NC_012563:29254722925472296409938628Clostridium botulinum A2 str. Kyoto, complete genome7e-22113BLASTN svgBLASTP svg
NC_010418:18813818813820879920662Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete0815BLASTN svgBLASTP svg
NC_010520:496500*49650051930622807Clostridium botulinum A3 str. Loch Maree, complete genome8e-108398BLASTN svgBLASTP svg
NC_010520:11460001146000116884922850Clostridium botulinum A3 str. Loch Maree, complete genome7e-102379BLASTN svgBLASTP svg
NC_010674:65859665859667712118526Clostridium botulinum B str. Eklund 17B, complete genome9e-0660BLASTN svgBLASTP svg
NC_010516:3807780*3807780384035532576Clostridium botulinum B1 str. Okra, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010516:514000*51400053623322234Clostridium botulinum B1 str. Okra, complete genome2e-105391BLASTN svgBLASTP svg
NC_010516:3368951*3368951339250323553Clostridium botulinum B1 str. Okra, complete genome7e-31143BLASTN svgBLASTP svg
NC_008593:153014*15301417175318740Clostridium novyi NT, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_008261:676000*67600070224526246Clostridium perfringens ATCC 13124, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_008262:654000*65400067859924600Clostridium perfringens SM101, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_003366:72885972885975493526077Clostridium perfringens str. 13, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_004557:45589545589547680920915Clostridium tetani E88, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_021184:14800014800017152023521Desulfotomaculum gibsoniae DSM 7213, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_015930:18969*189693942820460Lactococcus garvieae ATCC 49156, complete genome9e-0660BLASTN svgBLASTP svg
NC_015680:1315040*1315040135525840219Pyrococcus yayanosii CH1 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_011978:15006631500663152082120159Thermotoga neapolitana DSM 4359, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_004344:25747125747127832220852Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,9e-0660BLASTN svgBLASTP svg