Pre_GI: BLASTP Hits

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Query: NC_008258:269806:272894 Shigella flexneri 5 str. 8401, complete genome

Start: 272894, End: 273478, Length: 585

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002927:3827211:383697238369723837550579Bordetella bronchiseptica RB50, complete genomeputative phage tail protein5e-0857.4
NC_002937:2933000:295113929511392951765627Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completetail protein, putative6e-1684
NC_002937:255790:259120259120259746627Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completetail protein, putative6e-1684
NC_009778:1556222:158586115858611586433573Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein3e-46184
NC_009436:2776410:278999227899922790573582Enterobacter sp. 638, complete genomehypothetical protein1e-78291
NC_008563:2909945:292325629232562923840585Escherichia coli APEC O1, complete genomehypothetical protein5e-101366
NC_009800:2049346:206986320698632070537675Escherichia coli HS, complete genomehypothetical protein2e-1995.5
NC_011750:2928990:294005329400532940637585Escherichia coli IAI39 chromosome, complete genomehypothetical protein3e-94343
NC_000913:1188999:120613612061361206720585Escherichia coli K12, complete genomee14 prophage; conserved protein1e-101368
NC_011742:2823000:284056628405662841150585Escherichia coli S88 chromosome, complete genomehypothetical protein5e-101366
NC_007946:2894793:290822929082292908813585Escherichia coli UTI89, complete genomebacteriophage V tail protein5e-101366
AC_000091:1191353:120849012084901209074585Escherichia coli W3110 DNA, complete genomehypothetical protein1e-101368
NC_011740:621408:624496624496625080585Escherichia fergusonii ATCC 35469, complete genomeconserved hypothetical protein; e14 prophage3e-102370
NC_011365:592256:631271631271631651381Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genome6e-0753.9
NC_012660:4558122:458101345810134581612600Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein2e-1272
NC_002947:4362271:438385543838554384499645Pseudomonas putida KT2440, complete genomehypothetical protein1e-1066.2
NC_015733:1398083:139999013999901400634645Pseudomonas putida S16 chromosome, complete genomehypothetical protein2e-1065.5
NC_011205:2137696:215093821509382151525588Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853tail protein5e-54210
NC_011294:2009388:202263120226312023218588Salmonella enterica subsp. enterica serovar Enteritidis strphage tail protein5e-54210
NC_010102:1779707:180219918021991802786588Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein5e-54210
NC_011094:2115750:212959621295962130183588Salmonella enterica subsp. enterica serovar Schwarzengrund strtail protein5e-54210
NC_016810:2027311:204391320439132044500588Salmonella enterica subsp. enterica serovar Typhimurium strputative bacteriophage tail protein5e-54210
NC_016856:2085283:209775020977502098337588Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Shypothetical protein5e-54210
NC_017046:2026672:204327420432742043861588Salmonella enterica subsp. enterica serovar Typhimurium str. 798bacteriophage tail protein5e-54210
NC_016857:2027311:204391320439132044500588Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative tail protein5e-54210
NC_016863:2029340:204594220459422046529588Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1hypothetical protein5e-54210
NC_007712:1182518:119455111945511195150600Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein4e-51201
NC_007712:4023516:403280940328094033297489Sodalis glossinidius str. 'morsitans', complete genomeputative phage tail protein9e-34142
NC_014228:3282500:331231833123183312899582Xenorhabdus nematophila ATCC 19061, complete genomeputative prophage protein2e-0755.5