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Query: NC_008150:1384102:1393990 Yersinia pestis Antiqua, complete genome

Start: 1393990, End: 1394214, Length: 225

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:3535786:354987835498783550102225Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-28124
NC_005810:1663672:167816616781661678390225Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-28124
NC_006155:2084669:209253720925372092761225Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-28124
NC_010159:2128157:213795521379552138179225Yersinia pestis Angola, complete genomehypothetical protein1e-28124
NC_003143:2101902:211091121109112111135225Yersinia pestis CO92, complete genomehypothetical protein1e-28124
NC_010465:2582080:259126725912672591491225Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein1e-28124
NC_009381:1414985:142505014250501425274225Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-28124
NC_009708:2537557:256130325613032561527225Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-28124
NC_008800:2013450:201767020176702017894225Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein4e-26116
NC_015224:2061951:207410720741072074331225Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein4e-26116
NC_020064:1854589:185888618588861859110225Serratia marcescens FGI94, complete genomeProtein of unknown function (DUF2594)2e-1994
NC_015566:1941407:194733219473321947556225Serratia sp. AS12 chromosome, complete genomehypothetical protein4e-1993.2
NC_004547:3207776:323176832317683231992225Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein8e-1785.5
NC_016816:2953530:298250329825032982727225Pantoea ananatis LMG 5342, complete genomehypothetical protein6e-1579.3
NC_014837:1570500:157402215740221574246225Pantoea sp. At-9b chromosome, complete genomehypothetical protein8e-1579
NC_014500:3097362:312334531233453123569225Dickeya dadantii 3937 chromosome, complete genomeputative cytoplasmic protein3e-1477
NC_013592:1668092:167966416796641679888225Dickeya dadantii Ech586, complete genomeProtein of unknown function DUF25943e-1477
NC_012912:1701231:173587117358711736095225Dickeya zeae Ech1591, complete genomehypothetical protein5e-1476.3
NC_009436:2685910:270072227007222700946225Enterobacter sp. 638, complete genomehypothetical protein8e-1475.9
NC_012779:2184927:218797421879742188198225Edwardsiella ictaluri 93-146, complete genomehypothetical protein9e-1475.5
NC_013508:2130681:216049721604972160721225Edwardsiella tarda EIB202, complete genomehypothetical protein1e-1375.1
NC_016514:2950860:295381129538112954035225Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YecF2e-1374.3
NC_012880:1711062:171855917185591718783225Dickeya dadantii Ech703, complete genomehypothetical protein1e-1271.6