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Query: NC_008149:1002453 Yersinia pestis Nepal516, complete genome

Start: 1002453, End: 1027314, Length: 24862

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from Nepal. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008150:30150003015000303859923600Yersinia pestis Antiqua, complete genome025280BLASTN svgBLASTP svg
NC_003143:35834683583468360515221685Yersinia pestis CO92, complete genome025280BLASTN svgBLASTP svg
NC_005810:75434075434077859924260Yersinia pestis biovar Microtus str. 91001, complete genome025270BLASTN svgBLASTP svg
NC_004088:10754541075454109916823715Yersinia pestis KIM, complete genome025260BLASTN svgBLASTP svg
NC_006155:10742981074298109520420907Yersinia pseudotuberculosis IP 32953, complete genome024620BLASTN svgBLASTP svg
NC_010634:10564411056441108059924159Yersinia pseudotuberculosis PB1/+, complete genome024590BLASTN svgBLASTP svg
NC_010465:35970003597000361924222243Yersinia pseudotuberculosis YPIII, complete genome024180BLASTN svgBLASTP svg
NC_010159:35023503502350352559923250Yersinia pestis Angola, complete genome020730BLASTN svgBLASTP svg
NC_020211:996497*996497103223335737Serratia marcescens WW4, complete genome4e-104387BLASTN svgBLASTP svg
NC_012917:3684840*3684840370871823879Pectobacterium carotovorum subsp. carotovorum PC1, complete genome2e-72281BLASTN svgBLASTP svg
NC_013421:3752619*3752619377249719879Pectobacterium wasabiae WPP163, complete genome1e-70276BLASTN svgBLASTP svg
NC_004547:3866439*3866439389314026702Erwinia carotovora subsp. atroseptica SCRI1043, complete genome9e-62246BLASTN svgBLASTP svg
NC_007384:307013*30701333111524103Shigella sonnei Ss046, complete genome3e-37165BLASTN svgBLASTP svg
NC_008563:28713628713630584318708Escherichia coli APEC O1, complete genome7e-35157BLASTN svgBLASTP svg
NC_020063:3690308*3690308375363663329Enterobacteriaceae bacterium strain FGI 57, complete genome1e-33153BLASTN svgBLASTP svg
NC_020260:3004500*3004500302796523466Cronobacter sakazakii Sp291, complete genome6e-26127BLASTN svgBLASTP svg
NC_013282:923500*92350094659923100Cronobacter turicensis, complete genome6e-26127BLASTN svgBLASTP svg
NC_006905:368942*36894239327424333Salmonella enterica subsp. enterica serovar Choleraesuis str6e-26127BLASTN svgBLASTP svg
NC_004631:2584244*2584244260559921356Salmonella enterica subsp. enterica serovar Typhi Ty2, complete1e-23119BLASTN svgBLASTP svg
NC_011083:374000*37400039609922100Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,1e-23119BLASTN svgBLASTP svg
NC_014121:1101093*1101093113435733265Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete6e-23117BLASTN svgBLASTP svg
NC_010498:301000*30100034338442385Escherichia coli SMS-3-5, complete genome6e-23117BLASTN svgBLASTP svg
NC_009800:289000*28900031038921390Escherichia coli HS, complete genome6e-23117BLASTN svgBLASTP svg
NC_004431:364000*36400042492660927Escherichia coli CFT073, complete genome2e-22115BLASTN svgBLASTP svg
NC_004741:310382*31038233778027399Shigella flexneri 2a str. 2457T, complete genome2e-22115BLASTN svgBLASTP svg
NC_007946:289425*28942536040270978Escherichia coli UTI89, complete genome2e-22115BLASTN svgBLASTP svg
NC_021066:3028421*3028421305110422684Raoultella ornithinolytica B6, complete genome2e-22115BLASTN svgBLASTP svg
NC_014500:3744705*3744705376630221598Dickeya dadantii 3937 chromosome, complete genome1e-20109BLASTN svgBLASTP svg
NC_009648:293052*29305232674733696Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome9e-19103BLASTN svgBLASTP svg
NC_010506:4404377*4404377442416819792Shewanella woodyi ATCC 51908, complete genome9e-19103BLASTN svgBLASTP svg
NC_013716:357928*35792840652048593Citrobacter rodentium ICC168, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_004337:309833*30983333864628814Shigella flexneri 2a str. 301, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_003197:36743036743038660919180Salmonella typhimurium LT2, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_013508:876431*87643191551339083Edwardsiella tarda EIB202, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_012779:91600091600093379317794Edwardsiella ictaluri 93-146, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_015276:28520102852010287194819939Marinomonas mediterranea MMB-1 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
CP002516:3863932*3863932388609922168Escherichia coli KO11, complete genome5e-0867.9BLASTN svgBLASTP svg