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Query: NC_007797:441782 Anaplasma phagocytophilum HZ, complete genome

Start: 441782, End: 460512, Length: 18731

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_006833:806467*80646782648920023Wolbachia endosymbiont strain TRS of Brugia malayi, complete6e-1073.8BLASTN svgBLASTP svg
NC_014774:1019273*1019273103809918827Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, complete9e-0969.9BLASTN svgBLASTP svg
NC_007799:55590055590058009124192Ehrlichia chaffeensis str. Arkansas, complete genome6e-0763.9BLASTN svgBLASTP svg