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Query: NC_007797:1451804 Anaplasma phagocytophilum HZ, complete genome

Start: 1451804, End: 1477999, Length: 26196

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_005295:21995219954409922105Ehrlichia ruminantium str. Welgevonden, complete genome2e-99371BLASTN svgBLASTP svg
NC_006831:450045002319218693Ehrlichia ruminantium str. Gardel, complete genome2e-99371BLASTN svgBLASTP svg
NC_013532:85371*8537110357718207Anaplasma centrale str. Israel, complete genome8e-78299BLASTN svgBLASTP svg
NC_012026:1135041*1135041116545030410Anaplasma marginale str. Florida, complete genome3e-68268BLASTN svgBLASTP svg
NC_002978:4973*49733067725705Wolbachia endosymbiont of Drosophila melanogaster, complete genome1e-61246BLASTN svgBLASTP svg
NC_004842:1132441*1132441116265130211Anaplasma marginale str. St. Maries, complete genome4e-61244BLASTN svgBLASTP svg
NC_007797:107950*10795013067222723Anaplasma phagocytophilum HZ, complete genome9e-59236BLASTN svgBLASTP svg
NC_012416:4973*49733030125329Wolbachia sp. wRi, complete genome2e-56228BLASTN svgBLASTP svg
NC_004842:1031020*1031020105312922110Anaplasma marginale str. St. Maries, complete genome4e-21111BLASTN svgBLASTP svg
NC_004842:95005895005897658326526Anaplasma marginale str. St. Maries, complete genome4e-21111BLASTN svgBLASTP svg
NC_012026:96000096000098218522186Anaplasma marginale str. Florida, complete genome9e-19103BLASTN svgBLASTP svg
NC_012026:21385*213854495323569Anaplasma marginale str. Florida, complete genome9e-19103BLASTN svgBLASTP svg
NC_012026:1034724*1034724105518720464Anaplasma marginale str. Florida, complete genome9e-19103BLASTN svgBLASTP svg
NC_007798:652317*65231769011637800Neorickettsia sennetsu str. Miyayama, complete genome4e-18101BLASTN svgBLASTP svg
NC_007797:914500*91450093405419555Anaplasma phagocytophilum HZ, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_004842:1081271*1081271110423422964Anaplasma marginale str. St. Maries, complete genome2e-0765.9BLASTN svgBLASTP svg