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Query: NC_007797:692944:702931 Anaplasma phagocytophilum HZ, complete genome

Start: 702931, End: 705570, Length: 2640

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014375:1242750:1269643126964312733323690Brevundimonas subvibrioides ATCC 15264 chromosome, complete genomegene transfer agent (GTA) orfg15, like protein5e-60233
NC_016078:715005:7249187249187286763759Pelagibacterium halotolerans B2 chromosome, complete genomephage Host Specificity protein5e-58226
NC_007406:857625:8775698775698815103942Nitrobacter winogradskyi Nb-255, complete genomegene transfer agent (GTA) like protein4e-44180
NC_014034:995661:1014191101419110181623972Rhodobacter capsulatus SB1003 chromosome, complete genomehypothetical protein9e-40166
NC_008687:45967:5070550705545953891Paracoccus denitrificans PD1222 chromosome 2, complete sequenceputative phage host specificity protein1e-33145
NC_003911:2899435:2913938291393829179023965Silicibacter pomeroyi DSS-3, complete genome2e-33145
NC_014034:1816000:1828861182886118327753915Rhodobacter capsulatus SB1003 chromosome, complete genomehypothetical protein4e-31137
NC_020911:2793234:2800315280031528042413927Octadecabacter antarcticus 307, complete genomeputative gene transfer agent protein7e-24113
NC_003911:2379254:2393491239349123974173927Silicibacter pomeroyi DSS-3, complete genomehypothetical protein8e-23109
NC_015593:203000:2221002221002243012202Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completehypothetical protein3e-20101
NC_008687:256692:2566922566922596822991Paracoccus denitrificans PD1222 chromosome 2, complete sequencegene transfer agent (GTA) like protein4e-1894
NC_011365:592256:6354476354476382422796Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genomehypothetical protein3e-0654.7