Pre_GI: BLASTP Hits

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Query: NC_005945:3992600:4001812 Bacillus anthracis str. Sterne, complete genome

Start: 4001812, End: 4002912, Length: 1101

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009725:3602632:3607584360758436088701287Bacillus amyloliquefaciens FZB42, complete genomeRocG5e-1065.9
NC_007530:3992228:4001440400144040025401101Bacillus anthracis str. 'Ames Ancestor', complete genomeleucine dehydrogenase0684
NC_012659:3992684:4001340400134040024401101Bacillus anthracis str. A0248, complete genomeleucine dehydrogenase0684
NC_003997:3993223:4001313400131340024131101Bacillus anthracis str. Ames, complete genomeleucine dehydrogenase0684
NC_011773:3982008:3993663399366339947631101Bacillus cereus AH820 chromosome, complete genomeleucine dehydrogenase0684
NC_003909:3941282:3950125395012539512251101Bacillus cereus ATCC 10987, complete genomeleucine dehydrogenase0682
NC_004722:4117459:4125770412577041268701101Bacillus cereus ATCC 14579, complete genomeLeucine dehydrogenase0682
NC_011725:4159000:4167927416792741690271101Bacillus cereus B4264 chromosome, complete genomeleucine dehydrogenase0682
NC_014335:3902155:3910835391083539119351101Bacillus cereus biovar anthracis str. CI chromosome, completeleucine dehydrogenase0684
NC_006274:4031246:4039556403955640406561101Bacillus cereus E33L, complete genomeleucine dehydrogenase0683
NC_016779:3913627:3922843392284339239431101Bacillus cereus F837/76 chromosome, complete genomeleucine dehydrogenase0684
NC_011772:4125996:4136169413616941372691101Bacillus cereus G9842, complete genomeleucine dehydrogenase0682
NC_011969:3879412:3891287389128738923871101Bacillus cereus Q1 chromosome, complete genomeleucine dehydrogenase0684
NC_009674:2923707:2932018293201829331181101Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeGlu/Leu/Phe/Val dehydrogenase0670
NC_014171:4039120:4048495404849540495951101Bacillus thuringiensis BMB171 chromosome, complete genomeleucine dehydrogenase0682
NC_017208:4166008:4174320417432041754201101Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeleucine dehydrogenase0682
NC_005957:3975192:3987917398791739890171101Bacillus thuringiensis serovar konkukian str. 97-27, completeleucine dehydrogenase0684
NC_008600:3976045:3987712398771239888121101Bacillus thuringiensis str. Al Hakam, complete genomeleucine dehydrogenase0684
NC_010184:4021688:4033341403334140344411101Bacillus weihenstephanensis KBAB4, complete genomeGlu/Leu/Phe/Val dehydrogenase0679
NC_010830:475248:4903684903684914741107Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein1e-83310
NC_014010:484000:4841114841114855141404Candidatus Puniceispirillum marinum IMCC1322 chromosome, completeGlu/Leu/Phe/Val dehydrogenase3e-0963.5
NC_011831:1693935:1713921171392117152071287Chloroflexus aggregans DSM 9485, complete genomeGlu/Leu/Phe/Val dehydrogenase9e-0755.1
NC_013739:717352:7469427469427482071266Conexibacter woesei DSM 14684, complete genomeGlu/Leu/Phe/Val dehydrogenase2e-0860.5
NC_010694:1966676:1982546198254619838201275Erwinia tasmaniensis, complete genomeGlutamate dehydrogenase1e-0654.3
NC_008278:132000:1331081331081341781071Frankia alni ACN14a, complete genomeValine dehydrogenase (ValDH)2e-79296
NC_012793:2337776:2355585235558523566881104Geobacillus sp. WCH70, complete genomeGlu/Leu/Phe/Val dehydrogenase2e-169595
NC_016593:2447938:2447938244793824490411104Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completeleucine dehydrogenase1e-168592
NC_013440:3112340:3136048313604831373821335Haliangium ochraceum DSM 14365, complete genomeGlu/Leu/Phe/Val dehydrogenase4e-1272.8
NC_013743:3020687:3020687302068730219821296Haloterrigena turkmenica DSM 5511, complete genomeGlu/Leu/Phe/Val dehydrogenase3e-0653.1
NC_015520:330500:3495703495703508171248Mahella australiensis 50-1 BON chromosome, complete genomeglutamate dehydrogenase (NAD/NADP)7e-0962
NC_012988:4387735:4389103438910343903651263Methylobacterium extorquens DM4, complete genomeglutamate dehydrogenase2e-1170.1
NC_011894:957897:9728129728129740681257Methylobacterium nodulans ORS 2060, complete genomeGlu/Leu/Phe/Val dehydrogenase2e-0757
NC_015945:218326:2183262183262196181293Muricauda ruestringensis DSM 13258 chromosome, complete genomeglutamate dehydrogenase (NAD(P)(+))4e-1375.9
NC_015711:7265439:7277618727761872791681551Myxococcus fulvus HW-1 chromosome, complete genomeGlu/Leu/Phe/Val dehydrogenase family protein1e-0964.3
NC_020126:6190662:6203170620317062047201551Myxococcus stipitatus DSM 14675, complete genomeGlu/Leu/Phe/Val dehydrogenase5e-1168.9
NC_008095:5312926:5325253532525353267821530Myxococcus xanthus DK 1622, complete genomeGlu/Leu/Phe/Val dehydrogenase family protein1e-0964.3
NC_010718:2492895:2499424249942425005001077Natranaerobius thermophilus JW/NM-WN-LF, complete genomeleucine dehydrogenase4e-99361
NC_013923:45876:5509455094563741281Natrialba magadii ATCC 43099 plasmid pNMAG01, complete sequenceGlu/Leu/Phe/Val dehydrogenase3e-0756.2
NC_019962:1750497:1855425185542518566931269Natrinema pellirubrum DSM 15624, complete genomeglutamate dehydrogenase/leucine dehydrogenase4e-0652.8
NC_019962:1750497:1766456176645617677511296Natrinema pellirubrum DSM 15624, complete genomeglutamate dehydrogenase/leucine dehydrogenase6e-0858.9
NC_010003:1724500:1724519172451917258141296Petrotoga mobilis SJ95, complete genomeGlu/Leu/Phe/Val dehydrogenase4e-0859.3
NC_008781:1507384:1528701152870115300201320Polaromonas naphthalenivorans CJ2, complete genomeGlu/Leu/Phe/Val dehydrogenase, C terminal7e-0962
NC_008228:3608909:3621586362158636227011116Pseudoalteromonas atlantica T6c, complete genomeGlu/Leu/Phe/Val dehydrogenase, dimerisation region1e-84313
NC_008027:4889662:4916358491635849173771020Pseudomonas entomophila L48, complete genomeleucine dehydrogenase4e-63242
NC_020209:397376:4041964041964052151020Pseudomonas poae RE*1-1-14, complete genomeleucine dehydrogenase2e-63243
NC_010501:908000:9130689130689140871020Pseudomonas putida W619, complete genomeGlu/Leu/Phe/Val dehydrogenase dimerisation region2e-58226
NC_008314:477722:5082855082855093821098Ralstonia eutropha H16 chromosome 2, complete sequenceleucine dehydrogenase1e-70266
NC_020541:2694836:2714721271472127158241104Rhodanobacter sp. 2APBS1, complete genomeglutamate dehydrogenase/leucine dehydrogenase1e-101370
NC_012522:3224526:3236336323633632376551320Rhodococcus opacus B4, complete genomeglutamate dehydrogenase2e-0653.5
NC_008268:3335035:3350853335085333519321080Rhodococcus sp. RHA1, complete genomepossible phenylalanine dehydrogenase2e-20100
NC_013521:940495:9471749471749485531380Sanguibacter keddieii DSM 10542, complete genomeglutamate dehydrogenase/leucine dehydrogenase1e-0861.2
NC_020164:2329340:2345814234581423468811068Staphylococcus warneri SG1, complete genomeleucine dehydrogenase2e-106385
NC_017275:568722:5835165835165847751260Sulfolobus islandicus HVE10/4 chromosome, complete genomeGlu/Leu/Phe/Val dehydrogenase2e-1480.5
NC_002754:1749834:1749834174983417511381305Sulfolobus solfataricus P2, complete genomeNAD specific glutamate dehydrogenase (gdhA-3)9e-1581.6
NC_008319:262894:2806572806572817211065Synechococcus sp. CC9311, complete genomepossible leucine dehydrogenase1e-1687.8
NC_018870:484000:4906464906464917251080Thermacetogenium phaeum DSM 12270 chromosome, complete genomeleucine dehydrogenase Ldh3e-85315
NC_014538:1942500:1952615195261519536821068Thermoanaerobacter sp. X513 chromosome, complete genomeGlu/Leu/Phe/Val dehydrogenase dimerization region2e-129462
NC_003869:2099000:2112645211264521137241080Thermoanaerobacter tengcongensis MB4, complete genomeGlutamate dehydrogenase/leucine dehydrogenase3e-125448
NC_015958:2206032:2233167223316722342341068Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomeGlu/Leu/Phe/Val dehydrogenase dimerization region6e-130464