Pre_GI: BLASTP Hits

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Query: NC_005945:1103729:1121369 Bacillus anthracis str. Sterne, complete genome

Start: 1121369, End: 1121590, Length: 222

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1103737:111961411196141119829216Bacillus anthracis str. A0248, complete genomespore germination protein GerPF2e-0754.7
NC_012659:1103737:112137711213771121598222Bacillus anthracis str. A0248, complete genomespore germination protein GerPA2e-34144
NC_005945:1103729:111960611196061119821216Bacillus anthracis str. Sterne, complete genomespore germination protein GerPF2e-0754.7
NC_003909:1244000:126072512607251260946222Bacillus cereus ATCC 10987, complete genomespore germination protein GerPA3e-34143
NC_003909:1244000:125895812589581259173216Bacillus cereus ATCC 10987, complete genomespore germination protein GerPF2e-0754.7
NC_004722:1108649:112641411264141126635222Bacillus cereus ATCC 14579, complete genomeSpore germination protein PA3e-34143
NC_004722:1108649:112464911246491124870222Bacillus cereus ATCC 14579, complete genomeSpore germination protein PF2e-0754.7
NC_011725:1150779:116847511684751168696222Bacillus cereus B4264 chromosome, complete genomespore germination protein GerPA2e-34144
NC_011725:1150779:116671111667111166926216Bacillus cereus B4264 chromosome, complete genomespore germination protein GerPF2e-0754.7
NC_014335:1094000:111271911127191112940222Bacillus cereus biovar anthracis str. CI chromosome, completespore germination protein PA2e-34144
NC_014335:1094000:111095511109551111170216Bacillus cereus biovar anthracis str. CI chromosome, completespore germination protein PF2e-0754.7
NC_011772:1094534:111061311106131110828216Bacillus cereus G9842, complete genomespore germination protein GerPF2e-0754.7
NC_011772:1094534:111237711123771112598222Bacillus cereus G9842, complete genomespore germination protein GerPA2e-34144
NC_011969:1181302:119765211976521197864213Bacillus cereus Q1 chromosome, complete genomespore germination protein pa3e-32136
NC_011969:1181302:119588811958881196103216Bacillus cereus Q1 chromosome, complete genomespore germination protein pf2e-0754.7
NC_014171:1118000:113250311325031132718216Bacillus thuringiensis BMB171 chromosome, complete genomespore germination protein PF2e-0754.7
NC_017208:1147230:116320311632031163418216Bacillus thuringiensis serovar chinensis CT-43 chromosome, completespore germination protein PF8e-0752.4
NC_017208:1147230:116496711649671165188222Bacillus thuringiensis serovar chinensis CT-43 chromosome, completespore germination protein PA3e-34143
NC_010184:1114000:112852011285201128741222Bacillus weihenstephanensis KBAB4, complete genomespore germination protein GerPA4e-33140
NC_010184:1114000:112675711267571126972216Bacillus weihenstephanensis KBAB4, complete genomespore germination protein PF8e-0752.4