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Query: NC_005810:3272765:3288481 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 3288481, End: 3288942, Length: 462

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:3923804:392442739244273924888462Yersinia pestis KIM, complete genomehypothetical protein1e-86318
NC_006155:4062000:406298940629894063444456Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-85313
NC_008149:587689:607187607187607642456Yersinia pestis Nepal516, complete genomehypothetical protein2e-85313
NC_010634:4001154:400319540031954003650456Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-85313
NC_009381:460358:479583479583480038456Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-85313
NC_014029:729675:749166749166749621456Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-85313
NC_017154:671816:691318691318691773456Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-85313
NC_017160:676249:693505693505693960456Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-85313
NC_003143:675622:697667697667698071405Yersinia pestis CO92, complete genomehypothetical protein2e-75280
NC_005810:3272765:328794832879483288460513Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-33140
NC_004088:3923804:392490939249093925421513Yersinia pestis KIM, complete genomehypothetical protein2e-33140
NC_008149:587689:606690606690607160471Yersinia pestis Nepal516, complete genomehypothetical protein6e-33139
NC_008150:3495851:349585134958513496321471Yersinia pestis Antiqua, complete genomehypothetical protein6e-33139
NC_006155:4062000:406347140634714063941471Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein6e-33139
NC_003143:675622:697119697119697589471Yersinia pestis CO92, complete genomehypothetical protein6e-33139
NC_010634:4001154:400367740036774004147471Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein6e-33139
NC_009381:460358:479086479086479556471Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein6e-33139
NC_014029:729675:748669748669749139471Yersinia pestis Z176003 chromosome, complete genomehypothetical protein6e-33139
NC_017154:671816:690821690821691291471Yersinia pestis D106004 chromosome, complete genomehypothetical protein6e-33139
NC_017160:676249:693008693008693478471Yersinia pestis D182038 chromosome, complete genomehypothetical protein6e-33139
NC_009708:633054:647929647929648402474Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein7e-26115
NC_010465:660207:675078675078675551474Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein7e-26115
NC_020064:1611820:162507116250711625547477Serratia marcescens FGI94, complete genomehypothetical protein2e-1064.7