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Query: NC_005126:2262500:2280636 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Start: 2280636, End: 2280950, Length: 315

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014500:3071764:307428530742853074584300Dickeya dadantii 3937 chromosome, complete genomeNegative regulator of flagellin synthesis flgM2e-1890.9
NC_012880:1765920:180726618072661807559294Dickeya dadantii Ech703, complete genomeanti-sigma-28 factor, FlgM7e-1579
NC_013508:1289159:133167613316761331972297Edwardsiella tarda EIB202, complete genomeanti-sigma28 factor2e-1787.4
NC_012962:3030726:303327730332773033579303Photorhabdus asymbiotica, complete genomenegative regulator of flagellin synthesis (anti-sigma-28 factor) flgm2e-47187
NC_010634:2004653:202764220276422027944303Yersinia pseudotuberculosis PB1/+, complete genomeanti-sigma-28 factor, FlgM3e-1890.5