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Query: NC_004851:191709:220300 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence

Start: 220300, End: 221247, Length: 948

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. Causes enteric disease. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010067:1655815:167595116759511676919969Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein2e-113409
NC_011747:115864:129836129836130789954Escherichia coli S88 plasmid pECOS88, complete sequenceouter membrane protease3e-106385
NC_013941:733286:743785743785744738954Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeprotease VII3e-106385
AP010958:604719:617011617011617964954Escherichia coli O103:H2 str. 12009 DNA, complete genomeputative outer membrane protease OmpT precursor3e-106385
NC_011415:644811:657248657248658201954Escherichia coli SE11 chromosome, complete genomeouter membrane protease3e-106385
NC_013353:604719:617011617011617964954Escherichia coli O103:H2 str. 12009, complete genomeouter membrane protease OmpT precursor3e-106385
NC_013361:649518:660843660843661796954Escherichia coli O26:H11 str. 11368 chromosome, complete genomeprotease3e-106385
AC_000091:558920:583903583903584856954Escherichia coli W3110 DNA, complete genomeouter membrane protease VII2e-106385
NC_010473:623810:636495636495637448954Escherichia coli str. K-12 substr. DH10B, complete genomeDLP12 prophage; outer membrane protease VII (outer membrane protein 3b)2e-106385
NC_000913:558920:583903583903584856954Escherichia coli K12, complete genomeDLP12 prophage; outer membrane protease VII (outer membrane protein 3b)2e-106385
NC_010473:498252:523235523235524188954Escherichia coli str. K-12 substr. DH10B, complete genomeDLP12 prophage; outer membrane protease VII (outer membrane protein 3b)2e-106385
NC_012759:461680:486663486663487616954Escherichia coli BW2952 chromosome, complete genomeouter membrane protease2e-106385
NC_011751:680417:690046690046690999954Escherichia coli UMN026 chromosome, complete genomeouter membrane protease3e-106384
NC_008563:1505405:151755815175581518520963Escherichia coli APEC O1, complete genomeouter membrane protease2e-105382
NC_009436:2056000:206169920616992062637939Enterobacter sp. 638, complete genomeouter membrane protease6e-61234
NC_013971:817284:832824832824833765942Erwinia amylovora ATCC 49946 chromosome, complete genomeouter membrane protease7e-60231
NC_013961:2932348:293762029376202938558939Erwinia amylovora, complete genomeIcsP/SopA5e-60231
NC_013961:2932348:294017729401772941115939Erwinia amylovora, complete genomeIcsP/SopA5e-60231
NC_013971:817284:830267830267831208942Erwinia amylovora ATCC 49946 chromosome, complete genomeouter membrane protease1e-59230
NC_011147:529458:535987535987536925939Salmonella enterica subsp. enterica serovar Paratyphi A strouter membrane protease1e-58226
NC_006511:529424:535953535953536891939Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCouter membrane protease E1e-58226
NC_012125:1330066:133357713335771334515939Salmonella enterica subsp. enterica serovar Paratyphi C strainouter membrane protease2e-58226
NC_004631:531254:537782537782538720939Salmonella enterica subsp. enterica serovar Typhi Ty2, completeouter membrane protease E3e-58225
NC_003198:2453074:246599224659922466930939Salmonella enterica subsp. enterica serovar Typhi str. CT18,outer membrane protease E3e-58225
NC_016832:531208:537736537736538674939Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Coagulase/fibrinolysin3e-58225
NC_011205:2621415:263219626321962633134939Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853outer membrane protease3e-58225
NC_011294:2492168:250510825051082506046939Salmonella enterica subsp. enterica serovar Enteritidis strouter membrane protease3e-58225
NC_011083:2542876:256318625631862564124939Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,protease 73e-58225
NC_016831:531404:537932537932538870939Salmonella enterica subsp. enterica serovar Gallinarum/pullorumouter membrane protease E8e-58224
NC_011274:2483038:249600724960072496945939Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91outer membrane protease8e-58224
NC_010158:1:666366637601939Yersinia pestis Angola plasmid pMT-pPCP, complete sequenceplasminogen activator Pla2e-57223
NC_010158:1:162711627117209939Yersinia pestis Angola plasmid pMT-pPCP, complete sequenceplasminogen activator Pla2e-57223
NC_015761:2373967:239237723923772393315939Salmonella bongori NCTC 12419, complete genomeouter membrane protease E5e-57221