Pre_GI: BLASTP Hits

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Query: NC_004741:3240909:3240909 Shigella flexneri 2a str. 2457T, complete genome

Start: 3240909, End: 3242273, Length: 1365

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a highly virulent strain that has been widely used for genetic and clinical research. Causes enteric disease. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3289853:3289853328985332912231371Shigella flexneri 2002017 chromosome, complete genomeputative L-serine deaminase0908
NC_004337:3249791:3249791324979132511551365Shigella flexneri 2a str. 301, complete genomeputative L-serine deaminase0907
NC_010498:3488513:3488513348851334898831371Escherichia coli SMS-3-5, complete genomeL-serine ammonia-lyase TdcG0904
NC_011751:3710786:3713731371373137150951365Escherichia coli UMN026 chromosome, complete genomeL-serine dehydratase 30902
CU928160:3344746:3344746334474633461101365Escherichia coli IAI1 chromosome, complete genomeL-serine dehydratase 30902
CP002516:613462:6287206287206300841365Escherichia coli KO11, complete genomeL-serine dehydratase 10902
NC_011748:3608917:3611861361186136132251365Escherichia coli 55989, complete genomeL-serine dehydratase 30902
NC_010658:3014371:3027485302748530288491365Shigella boydii CDC 3083-94, complete genomeL-serine ammonia-lyase TdcG0902
CU928145:3608917:3611861361186136132251365Escherichia coli 55989 chromosome, complete genomeL-serine dehydratase 30902
NC_008258:3224721:3224721322472132260851365Shigella flexneri 5 str. 8401, complete genomeputative L-serine dehydratase0902
NC_011741:3344746:3344746334474633461101365Escherichia coli IAI1 chromosome, complete genomeL-serine dehydratase 30902
NC_016902:613462:6287206287206300841365Escherichia coli KO11FL chromosome, complete genomeL-serine dehydratase 10902
NC_011750:3768692:3771636377163637730001365Escherichia coli IAI39 chromosome, complete genomeL-serine dehydratase 30900
NC_000913:3256307:3256307325630732576711365Escherichia coli K12, complete genomeL-serine dehydratase 30900
NC_009800:3307123:3307123330712333084871365Escherichia coli HS, complete genomeL-serine ammonia-lyase0900
NC_010468:613812:6309116309116322751365Escherichia coli ATCC 8739, complete genomeL-serine dehydratase 10900
NC_010473:3354052:3354052335405233554161365Escherichia coli str. K-12 substr. DH10B, complete genomeL-serine dehydratase 30900
NC_012759:3143455:3143455314345531448191365Escherichia coli BW2952 chromosome, complete genomeL-serine dehydratase 30900
NC_012947:630757:6478566478566492201365Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeL-serine dehydratase0900
NC_012967:3191319:3191319319131931926831365Escherichia coli B str. REL606 chromosome, complete genomeL-serine dehydratase 30900
NC_013941:3884725:3887669388766938890391371Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeL-serine ammonia-lyase TdcG0897
NC_011415:3523364:3526308352630835276721365Escherichia coli SE11 chromosome, complete genomeL-serine dehydratase0897
NC_002695:3994970:3997914399791439992781365Escherichia coli O157:H7 str. Sakai, complete genomeL-serine deaminase0895
CP002185:3475991:3475991347599134772891299Escherichia coli W, complete genomeL-serine dehydratase 30858
NC_014618:586240:6108486108486122121365Enterobacter cloacae SCF1 chromosome, complete genomeL-serine dehydratase 10773
NC_012779:2424967:2441692244169224430591368Edwardsiella ictaluri 93-146, complete genomeL-serine ammonia-lyase, putative0653
NC_013508:2356865:2381321238132123826881368Edwardsiella tarda EIB202, complete genomeL-serine dehydratase (deaminase), L-SD20653
NC_020064:1611820:1611820161182016131871368Serratia marcescens FGI94, complete genomeL-serine dehydratase, iron-sulfur-dependent, single chain form0645
NC_012668:2258854:2262686226268622640471362Vibrio cholerae MJ-1236 chromosome 1, complete sequenceL-serine dehydratase0640
NC_004603:1961432:1963738196373819650991362Vibrio parahaemolyticus RIMD 2210633 chromosome I, completeL-serine dehydratase 12e-177622
NC_016901:2916988:2932307293230729336831377Shewanella baltica OS678 chromosome, complete genomeL-serine dehydratase 11e-132473
NC_009997:2967521:2982840298284029842161377Shewanella baltica OS195, complete genomeL-serine dehydratase 11e-132473
NC_013595:1851226:1871277187127718726531377Streptosporangium roseum DSM 43021, complete genomeL-serine ammonia-lyase2e-128459
NC_016111:4588021:4603172460317246045391368Streptomyces cattleya NRRL 8057, complete genomeL-serine dehydratase4e-128458
NC_007948:4558000:4610728461072846121221395Polaromonas sp. JS666, complete genomeL-serine dehydratase 12e-126452
NC_013757:3012130:3020375302037530217511377Geodermatophilus obscurus DSM 43160, complete genomeL-serine dehydratase 15e-125448
NC_007908:1108494:1158783115878311602011419Rhodoferax ferrireducens T118, complete genomeL-serine dehydratase 13e-122438
NC_017955:3057592:3069527306952730708971371Modestobacter marinus, complete genomeL-serine ammonia-lyase4e-122438
NC_020829:5620826:5620826562082656222021377Pseudomonas denitrificans ATCC 13867, complete genomeL-serine dehydratase8e-121434
NC_014815:4621552:4646980464698046483501371Micromonospora sp. L5 chromosome, complete genomel-serine dehydratase 13e-119429
NC_007952:1587500:1601059160105916024531395Burkholderia xenovorans LB400 chromosome 2, complete sequenceIron-sulfur-dependent L-serine dehydratase single chain form7e-117421
NC_010617:55493:6869168691700671377Kocuria rhizophila DC2201, complete genomeL-serine dehydratase5e-113408
NC_005956:699206:7205107205107219071398Bartonella henselae str. Houston-1, complete genomeL-serine dehydratase4e-110398
NC_015510:4982255:5001526500152650029561431Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomeL-serine dehydratase 19e-108390
NC_016932:1246235:1253285125328512546911407Corynebacterium pseudotuberculosis 316 chromosome, complete genomeL-serine dehydratase2e-102373
NC_016783:1374464:1375099137509913764871389Corynebacterium diphtheriae INCA 402 chromosome, complete genomeL-serine dehydratase4e-102372
NC_014329:1261480:1268530126853012699361407Corynebacterium pseudotuberculosis FRC41 chromosome, completeL-serine dehydratase5e-102371
NC_016781:1261300:1268350126835012697561407Corynebacterium pseudotuberculosis 3/99-5 chromosome, completeL-serine dehydratase5e-102371
NC_017031:1261289:1268339126833912697451407Corynebacterium pseudotuberculosis P54B96 chromosome, completeL-serine dehydratase5e-102371
NC_017300:1258861:1265911126591112673171407Corynebacterium pseudotuberculosis 1002 chromosome, completeL-serine dehydratase5e-102371
NC_017301:1261167:1268217126821712696231407Corynebacterium pseudotuberculosis C231 chromosome, completeL-serine dehydratase5e-102371
NC_017303:1261311:1268361126836112697671407Corynebacterium pseudotuberculosis I19 chromosome, complete genomeL-serine dehydratase5e-102371
NC_017305:1258840:1265890126589012672961407Corynebacterium pseudotuberculosis PAT10 chromosome, completeL-serine dehydratase5e-102371
NC_016789:1334514:1396607139660713979951389Corynebacterium diphtheriae PW8 chromosome, complete genomeL-serine dehydratase5e-102371
NC_016801:1361597:1395927139592713973151389Corynebacterium diphtheriae C7 (beta) chromosome, complete genomeL-serine dehydratase5e-102371
NC_016785:1321700:1332382133238213337701389Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomeL-serine dehydratase3e-101369
NC_016800:1378728:1379363137936313807511389Corynebacterium diphtheriae BH8 chromosome, complete genomeL-serine dehydratase3e-101369
NC_016799:1343020:1406251140625114076391389Corynebacterium diphtheriae 31A chromosome, complete genomeL-serine dehydratase2e-101369
NC_016788:1349500:1350209135020913515971389Corynebacterium diphtheriae HC04 chromosome, complete genomeL-serine dehydratase5e-101368
NC_016802:1317365:1351697135169713530851389Corynebacterium diphtheriae HC02 chromosome, complete genomeL-serine dehydratase6e-101368
NC_009952:2217877:2240003224000322414151413Dinoroseobacter shibae DFL 12, complete genomeL-serine dehydratase5e-88325
NC_004757:427483:4301614301614315461386Nitrosomonas europaea ATCC 19718, complete genomeIron-sulfur-dependent L-serine dehydratase single chain form1e-87323
NC_009615:1553556:1558580155858015597911212Parabacteroides distasonis ATCC 8503 chromosome, complete genomeL-serine dehydratase2e-72273
NC_014364:394899:4636054636054648821278Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeL-serine ammonia-lyase6e-70265
NC_020409:621792:6270126270126283731362Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeL-serine dehydratase4e-68258
NC_014734:353159:3585403585403597511212Paludibacter propionicigenes WB4 chromosome, complete genomeL-serine ammonia-lyase2e-65249
NC_014632:11925:1581315813170211209Ilyobacter polytropus DSM 2926 chromosome, complete genomeserine dehydratase subunit alpha9e-65248
NC_014844:659829:6987796987796999991221Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomeL-serine ammonia-lyase6e-64245
NC_012121:837586:846023846023846892870Staphylococcus carnosus subsp. carnosus TM300, complete genomeputative L-serine dehydratase, iron-sulfur-dependent, alpha subunit9e-37154
UCMB5137:1159520:115864011586401159539900Bacillus atrophaeus UCMB-5137L-serine dehydratase subunit alpha3e-32140
NC_014103:4059905:407066340706634071550888Bacillus megaterium DSM319 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha4e-32139
NC_014098:3133440:314157931415793142460882Bacillus tusciae DSM 2912 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent, alpha subunit4e-32139
NC_018515:3909646:391504039150403915903864Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeL-serine ammonia-lyase2e-31137
NC_020291:902635:910672910672911547876Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeputative L-serine dehydratase, alpha chain2e-29130
NC_014654:549966:556603556603557475873Halanaerobium sp. 'sapolanicus' chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent, alpha subunit2e-29130
NC_015589:2878000:289801928980192898903885Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeL-serine dehydratase iron-sulfur-dependent subunit alpha1e-29130
NC_004193:1558551:156273915627391563614876Oceanobacillus iheyensis HTE831, complete genomeL-serine dehydratase alpha subunit2e-28127
NC_016745:546249:5588015588015602671467Oceanimonas sp. GK1 chromosome, complete genomeserine dehydratase subunit alpha3e-28126
NC_009699:1352211:136844613684461369336891Clostridium botulinum F str. Langeland chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha4e-28126
NC_016584:4905310:490995949099594910822864Desulfosporosinus orientis DSM 765 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha5e-28125
NC_002973:1846000:186626218662621867152891Listeria monocytogenes str. 4b F2365, complete genomeL-serine dehydratase, iron-sulfur-dependent, alpha subunit9e-27121
NC_015425:405058:422448422448423329882Clostridium botulinum BKT015925 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha7e-26119
NC_013893:511222:514935514935515831897Staphylococcus lugdunensis HKU09-01 chromosome, complete genomeL-serine dehydratase, alpha subunit4e-26119
NC_017353:505935:509648509648510544897Staphylococcus lugdunensis N920143, complete genomeputative L-serine dehydratase, alpha chain4e-26119
NC_012780:284336:285928285928286827900Eubacterium eligens ATCC 27750 plasmid unnamed, complete sequenceL-serine dehydratase3e-26119
NC_017095:1927118:193349319334931934365873Fervidobacterium pennivorans DSM 9078 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha1e-25117
NC_015707:1911431:191809119180911918981891Thermotoga thermarum DSM 5069 chromosome, complete genomeL-serine ammonia-lyase2e-24114
NC_015977:2966971:299122229912222992094873Roseburia hominis A2-183 chromosome, complete genomeL-serine dehydratase1e-24114
NC_019908:121178:156510156510157391882Brachyspira pilosicoli P43/6/78 chromosome, complete genomeL-serine dehydratase iron-sulfur-dependent subunit alpha1e-22108
NC_018607:921923:956772956772957653882Brachyspira pilosicoli B2904 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha1e-22108
NC_014330:505412:507374507374508255882Brachyspira pilosicoli 95/1000 chromosome, complete genomeL-serine dehydratase iron-sulfur-dependent subunit alpha1e-22108
NC_007576:299266:321630321630322523894Lactobacillus sakei subsp. sakei 23K, complete genomeL-serine dehydratase, alpha subunit (L-serine deaminase)2e-22107
NC_018528:697553:719555719555720436882Lactobacillus helveticus R0052 chromosome, complete genomeL-serine dehydratase subunit alpha7e-22105
NC_015697:116000:123744123744124625882Lactobacillus reuteri SD2112 chromosome, complete genomeL-serine ammonia-lyase subunit alpha6e-2099
NC_014624:287500:3052573052573068551599Eubacterium limosum KIST612 chromosome, complete genomeL-serine dehydratase6e-2099
NC_016642:1913432:1922354192235419236971344Pseudovibrio sp. FO-BEG1 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit alpha3e-1687
NC_002973:1846000:186728818672881867950663Listeria monocytogenes str. 4b F2365, complete genomeL-serine dehydratase, iron-sulfur-dependent, beta subunit3e-0757
NC_014103:4059905:407165140716514072313663Bacillus megaterium DSM319 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent subunit beta4e-0653.1
NC_012522:7837071:784571478457147845968255Rhodococcus opacus B4, complete genomehypothetical protein6e-0652.8
NC_015387:1091403:110429911042991104946648Marinithermus hydrothermalis DSM 14884 chromosome, complete genomeL-serine dehydratase, iron-sulfur-dependent, beta subunit8e-0652