Pre_GI: BLASTN Hits

Some Help

Query: NC_004565:20256 Clostridium tetani E88 plasmid pE88, complete sequence

Start: 20256, End: 39099, Length: 18844

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008593:18598611859861188348723627Clostridium novyi NT, complete genome8e-40172BLASTN svgBLASTP svg
NC_021182:3525523*3525523356673741215Clostridium pasteurianum BC1, complete genome1e-32149BLASTN svgBLASTP svg
NC_021182:3409199*3409199343177822580Clostridium pasteurianum BC1, complete genome1e-32149BLASTN svgBLASTP svg
NC_014393:503230*50323052309919870Clostridium cellulovorans 743B chromosome, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_014393:139690*13969016309923410Clostridium cellulovorans 743B chromosome, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_020291:58088565808856585259243737Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-0661.9BLASTN svgBLASTP svg
NC_010379:688068804619239313Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence2e-0661.9BLASTN svgBLASTP svg