Query: NC_004557:2475030 Clostridium tetani E88, complete genome
Start: 2475030, End: 2499536, Length: 24507
Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
---|
NC_008593:1797000* | 1797000 | 1822013 | 25014 | Clostridium novyi NT, complete genome | 1e-30 | 143 | BLASTN svg | BLASTP svg |
NC_014328:1108479 | 1108479 | 1126099 | 17621 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 2e-22 | 115 | BLASTN svg | BLASTP svg |
NC_015687:303810* | 303810 | 362543 | 58734 | Clostridium acetobutylicum DSM 1731 chromosome, complete genome | 3e-18 | 101 | BLASTN svg | BLASTP svg |
NC_003030:303812* | 303812 | 362547 | 58736 | Clostridium acetobutylicum ATCC 824, complete genome | 3e-18 | 101 | BLASTN svg | BLASTP svg |
NC_008261:2117207 | 2117207 | 2140235 | 23029 | Clostridium perfringens ATCC 13124, complete genome | 1e-17 | 99.6 | BLASTN svg | BLASTP svg |
NC_003366:1901898 | 1901898 | 1924407 | 22510 | Clostridium perfringens str. 13, complete genome | 1e-17 | 99.6 | BLASTN svg | BLASTP svg |
NC_019978:2036779* | 2036779 | 2059290 | 22512 | Halobacteroides halobius DSM 5150, complete genome | 8e-16 | 93.7 | BLASTN svg | BLASTP svg |
NC_018643:857911 | 857911 | 910390 | 52480 | Alpha proteobacterium HIMB5 chromosome, complete genome | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_010723:1014334 | 1014334 | 1033724 | 19391 | Clostridium botulinum E3 str. Alaska E43, complete genome | 5e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_021182:162236* | 162236 | 184613 | 22378 | Clostridium pasteurianum BC1, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_014393:1901688 | 1901688 | 1921797 | 20110 | Clostridium cellulovorans 743B chromosome, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_014934:2985273* | 2985273 | 3017099 | 31827 | Cellulophaga algicola DSM 14237 chromosome, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_010516:3466000 | 3466000 | 3488099 | 22100 | Clostridium botulinum B1 str. Okra, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_014538:187747* | 187747 | 206338 | 18592 | Thermoanaerobacter sp. X513 chromosome, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_019908:499929 | 499929 | 524502 | 24574 | Brachyspira pilosicoli P43/6/78 chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_018607:1463918 | 1463918 | 1486099 | 22182 | Brachyspira pilosicoli B2904 chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014330:139175 | 139175 | 157903 | 18729 | Brachyspira pilosicoli 95/1000 chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015847:909938 | 909938 | 932868 | 22931 | Methanococcus maripaludis XI chromosome, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_005791:837505 | 837505 | 860715 | 23211 | Methanococcus maripaludis S2, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |