Pre_GI: BLASTN Hits

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Query: NC_004557:2475030 Clostridium tetani E88, complete genome

Start: 2475030, End: 2499536, Length: 24507

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008593:1797000*1797000182201325014Clostridium novyi NT, complete genome1e-30143BLASTN svgBLASTP svg
NC_014328:11084791108479112609917621Clostridium ljungdahlii ATCC 49587 chromosome, complete genome2e-22115BLASTN svgBLASTP svg
NC_015687:303810*30381036254358734Clostridium acetobutylicum DSM 1731 chromosome, complete genome3e-18101BLASTN svgBLASTP svg
NC_003030:303812*30381236254758736Clostridium acetobutylicum ATCC 824, complete genome3e-18101BLASTN svgBLASTP svg
NC_008261:21172072117207214023523029Clostridium perfringens ATCC 13124, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_003366:19018981901898192440722510Clostridium perfringens str. 13, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_019978:2036779*2036779205929022512Halobacteroides halobius DSM 5150, complete genome8e-1693.7BLASTN svgBLASTP svg
NC_018643:85791185791191039052480Alpha proteobacterium HIMB5 chromosome, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_010723:10143341014334103372419391Clostridium botulinum E3 str. Alaska E43, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_021182:162236*16223618461322378Clostridium pasteurianum BC1, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014393:19016881901688192179720110Clostridium cellulovorans 743B chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014934:2985273*2985273301709931827Cellulophaga algicola DSM 14237 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_010516:34660003466000348809922100Clostridium botulinum B1 str. Okra, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_014538:187747*18774720633818592Thermoanaerobacter sp. X513 chromosome, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_019908:49992949992952450224574Brachyspira pilosicoli P43/6/78 chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_018607:14639181463918148609922182Brachyspira pilosicoli B2904 chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_014330:13917513917515790318729Brachyspira pilosicoli 95/1000 chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_015847:90993890993893286822931Methanococcus maripaludis XI chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_005791:83750583750586071523211Methanococcus maripaludis S2, complete genome3e-0661.9BLASTN svgBLASTP svg