Pre_GI: BLASTP Hits

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Query: NC_004557:806878:826235 Clostridium tetani E88, complete genome

Start: 826235, End: 827086, Length: 852

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014614:656000:656113656113656976864Clostridium sticklandii, complete genomeputative phospholipase1e-86319
NC_005945:754517:769266769266770120855Bacillus anthracis str. Sterne, complete genomephospholipase, putative1e-78293
NC_014219:2284000:229727522972752298129855Bacillus selenitireducens MLS10 chromosome, complete genomePatatin5e-71267
NC_014933:3715467:371546737154673716315849Bacteroides helcogenes P 36-108 chromosome, complete genomePatatin7e-59227
NC_014376:1842290:184412818441281844988861Clostridium saccharolyticum WM1 chromosome, complete genomePatatin6e-56218
NC_010674:370629:372614372614373456843Clostridium botulinum B str. Eklund 17B, complete genomephospholipase, patatin family3e-52205
NC_013170:1020339:102456610245661025507942Cryptobacterium curtum DSM 15641, complete genomepredicted esterase of the alpha-beta hydrolase superfamily3e-45182
NC_015975:1056731:106124910612491062127879Lactobacillus ruminis ATCC 27782 chromosome, complete genomeputative hydrolase2e-44179
NC_012704:696374:716057716057716986930Corynebacterium kroppenstedtii DSM 44385, complete genomeputative phospholipase3e-37155
NC_015673:1794590:179889117988911799772882Corynebacterium resistens DSM 45100 chromosome, complete genomeputative lysophospholipase2e-33142
NC_016516:15102:344563445635334879Propionibacterium acnes TypeIA2 P.acn33 chromosome, completephospholipase1e-32140
NC_014039:15236:3458434584356151032Propionibacterium acnes SK137 chromosome, complete genomephospholipase, patatin family1e-32140
NC_016512:15102:344563445635286831Propionibacterium acnes TypeIA2 P.acn17 chromosome, completephospholipase8e-28124
NC_016511:15100:344533445335283831Propionibacterium acnes TypeIA2 P.acn31 chromosome, completephospholipase8e-28124
NC_013716:5141269:5162030516203051631031074Citrobacter rodentium ICC168, complete genomepatatin-like phospholipase5e-23108
NC_013971:666730:6888416888416898931053Erwinia amylovora ATCC 49946 chromosome, complete genomepatatin-like phospholipase1e-20100
NC_013956:3641368:3676566367656636777981233Pantoea ananatis LMG 20103 chromosome, complete genomeYjjU2e-2099.4
NC_010554:2646806:2647585264758526486461062Proteus mirabilis HI4320, complete genomepatatin-like phospholipase1e-1997.1
NC_010694:715500:7360087360087370271020Erwinia tasmaniensis, complete genomeConserved hypothetical protein YjjU7e-1994.7
NC_012214:745302:7651587651587661861029Erwinia pyrifoliae Ep1/96, complete genomehypothetical protein YjjU4e-1892
NC_014618:4010689:4042469404246940435121044Enterobacter cloacae SCF1 chromosome, complete genomepatatin4e-1892
NC_013939:1625491:163880516388051639659855Deferribacter desulfuricans SSM1, complete genomehypothetical protein2e-1170.1
NC_013850:2103469:210492521049252105827903Klebsiella variicola At-22 chromosome, complete genomePatatin1e-0757.4
NC_010723:3530000:356788935678893568788900Clostridium botulinum E3 str. Alaska E43, complete genomephospholipase, patatin family1e-0757.4
NC_010674:3674739:371086337108633711762900Clostridium botulinum B str. Eklund 17B, complete genomephospholipase, patatin family2e-0756.6
NC_011297:767333:769312769312770244933Dictyoglomus thermophilum H-6-12, complete genomeesterase8e-0754.7
NC_009455:273519:312287312287313114828Dehalococcoides sp. BAV1 chromosome, complete genomepatatin1e-0654.3
NC_011661:938754:940730940730941662933Dictyoglomus turgidum DSM 6724, complete genomePatatin2e-0653.1
NC_015601:71471:747087470875616909Erysipelothrix rhusiopathiae str. Fujisawa, complete genomepatatin-like phospholipase7e-0651.6
NC_016609:7659853:767457676745767675349774Niastella koreensis GR20-10 chromosome, complete genomepatatin7e-0651.2