Pre_GI: BLASTP Hits

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Query: NC_004557:2607073:2625384 Clostridium tetani E88, complete genome

Start: 2625384, End: 2625977, Length: 594

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_020291:744329:7646177646177657141098Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeputative metal dependent phosphohydrolase, MobA- like'4e-22104
NC_013216:3625830:3629873362987336310991227Desulfotomaculum acetoxidans DSM 771, complete genomemetal dependent phosphohydrolase2e-2099.4
NC_009922:944538:962906962906963586681Alkaliphilus oremlandii OhILAs, complete genomeconserved hypothetical protein8e-1993.6
NC_008554:1623041:1626812162681216285871776Syntrophobacter fumaroxidans MPOB, complete genomemetal dependent phosphohydrolase1e-1789.4
NC_010718:2337209:234145923414592342187729Natranaerobius thermophilus JW/NM-WN-LF, complete genomeconserved hypothetical protein, possibly involved in molybdenum cofactor biosynthesis2e-1788.6
NC_009617:2304390:230701023070102307621612Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein3e-1788.2
NC_015519:426948:456861456861457439579Tepidanaerobacter sp. Re1 chromosome, complete genomeMobA-like protein2e-1685.5
NC_018664:3009166:303963130396313040209579Clostridium acidurici 9a chromosome, complete genomemolybdenum hydroxylase accessory protein, YgfJ family2e-1685.1
NC_014328:2643588:2649278264927826503841107Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative metal dependent phosphohydrolase2e-1685.1
NC_020409:1956485:1961687196168719628141128Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeMetal dependent phosphohydrolase7e-1580.5
NC_015737:2050219:206075020607502061355606Clostridium sp. SY8519, complete genomeMobA-like protein7e-1580.5
NC_015151:1872280:188373618837361884314579Vulcanisaeta moutnovskia 768-28 chromosome, complete genomeUDP-N-acetylglucosamine pyrophosphorylase8e-1580.1
NC_009454:1577319:160083416008341601427594Pelotomaculum thermopropionicum SI, complete genomeMobA-like protein2e-1479
NC_014829:988980:100891910089191009533615Bacillus cellulosilyticus DSM 2522 chromosome, complete genome4-diphosphocytidyl-2C-methyl-D-erythritol synthase2e-1478.6
NC_016751:1524848:152792615279261528483558Marinitoga piezophila KA3 chromosome, complete genomeMobA-like protein6e-1477.4
NC_021182:434351:438389438389438976588Clostridium pasteurianum BC1, complete genomemolybdenum hydroxylase accessory protein, YgfJ family1e-1376.3
NC_010674:1170264:119024111902411190918678Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein7e-1373.6
NC_009617:2304390:231156623115662312495930Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeLysR family transcriptional regulator3e-1272
NC_020210:2133996:219082021908202191425606Geobacillus sp. GHH01, complete genome4-diphosphocytidyl-2C-methyl-D-erythritol synthase1e-1066.6
NC_020210:1275031:134717213471721347819648Geobacillus sp. GHH01, complete genome4-diphosphocytidyl-2C-methyl-D-erythritol synthase1e-1066.2
NC_014831:1818968:182538018253801826081702Thermaerobacter marianensis DSM 12885 chromosome, complete genome4-diphosphocytidyl-2C-methyl-D- erythritolsynthase3e-1065.1
NC_013943:124500:132044132044132613570Denitrovibrio acetiphilus DSM 12809 chromosome, complete genomehypothetical protein4e-1064.7
NC_010125:955863:957857957857958513657Gluconacetobacter diazotrophicus PAl 5, complete genome4e-1064.7
NC_009922:411434:433705433705434277573Alkaliphilus oremlandii OhILAs, complete genomeconserved hypothetical protein6e-1063.9
NC_008701:1607419:161684416168441617404561Pyrobaculum islandicum DSM 4184, complete genomehypothetical protein1e-0962.8
NC_008571:505776:520875520875521480606Gramella forsetii KT0803, complete genomeMobA-like molybdenum cofactor biosynthesis prote in4e-0961.2
NC_007412:147757:152436152436153008573Anabaena variabilis ATCC 29413 plasmid C, complete sequencehypothetical protein4e-0961.2
NC_008027:2996947:301701230170123017575564Pseudomonas entomophila L48, complete genomehypothetical protein5e-0960.8
NC_002947:2809591:283034028303402830939600Pseudomonas putida KT2440, complete genomehypothetical protein9e-0960.1
NC_014960:1697818:1711044171104417124771434Anaerolinea thermophila UNI-1, complete genomehypothetical protein2e-0858.9
NC_007645:5160133:518944051894405190030591Hahella chejuensis KCTC 2396, complete genomeuncharacterized MobA-related protein7e-0857
NC_020063:2230000:224371022437102244309600Enterobacteriaceae bacterium strain FGI 57, complete genomeputative MobA-like protein1e-0756.2
NC_018643:320197:330873330873331442570Alpha proteobacterium HIMB5 chromosome, complete genomeCytidylyltransferase2e-0755.8
NC_020054:4625895:462858146285814629171591Fibrella aestuarina BUZ 2 drat genomehypothetical protein2e-0755.8
NC_016002:2825017:284089828408982841512615Pseudogulbenkiania sp. NH8B, complete genomeMobA-like protein2e-0652
NC_018870:115982:147011147011147628618Thermacetogenium phaeum DSM 12270 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein A4e-0651.6