Pre_GI: BLASTP Hits

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Query: NC_004557:2607073:2609418 Clostridium tetani E88, complete genome

Start: 2609418, End: 2611550, Length: 2133

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008262:654000:6735736735736756932121Clostridium perfringens SM101, complete genomehelicase, putative0640
NC_008261:676000:6953866953866975062121Clostridium perfringens ATCC 13124, complete genomeputative helicase0637
NC_003366:728859:7480767480767501962121Clostridium perfringens str. 13, complete genomehypothetical protein0634
NC_016012:104500:1170321170321191252094Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeATP-dependent DNA helicase1e-102374
NC_011898:3973627:3977028397702839793102283Clostridium cellulolyticum H10, complete genomesuperfamily I DNA helicase3e-81303
NC_008593:841291:8579148579148601992286Clostridium novyi NT, complete genomesuperfamily I DNA helicase5e-77289
NC_014334:1848340:1869908186990818721992292Lactobacillus casei str. Zhang chromosome, complete genomesuperfamily I DNA and RNA helicase1e-58228
NC_004567:343500:3840383840383863472310Lactobacillus plantarum WCFS1, complete genomeDNA helicase (putative)5e-54213
NC_012491:1187864:1187864118786411902242361Brevibacillus brevis NBRC 100599, complete genomeprobable DNA helicase involved in recombination4e-49196
NC_020291:4357425:4359233435923343614732241Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehelicase IV3e-48193
NC_017208:1050414:1066257106625710685932337Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeATP-dependent DNA helicase rep5e-46186
NC_011772:1011220:1023748102374810260842337Bacillus cereus G9842, complete genomehelicase, UvrD/Rep family4e-45183
NC_017200:1157835:1176271117627111786042334Bacillus thuringiensis serovar finitimus YBT-020 chromosome,helicase, UvrD/Rep family protein1e-44182
NC_016779:991298:1009000100900010113302331Bacillus cereus F837/76 chromosome, complete genomeUvrD/Rep family helicase1e-44182
NC_004722:1008500:1021931102193110242642334Bacillus cereus ATCC 14579, complete genomeATP-dependent DNA helicase rep2e-44181
NC_014171:1018338:1036689103668910390222334Bacillus thuringiensis BMB171 chromosome, complete genomeATP-dependent DNA helicase rep2e-44181
NC_011773:1050000:1069750106975010720802331Bacillus cereus AH820 chromosome, complete genomeUvrD/Rep family helicase2e-44181
NC_011969:1084000:1101280110128011036162337Bacillus cereus Q1 chromosome, complete genomeATP-dependent DNA helicase replicase1e-44181
NC_010184:1017000:1031326103132610336622337Bacillus weihenstephanensis KBAB4, complete genomeUvrD/REP helicase1e-44181
NC_011725:1032500:1048278104827810506112334Bacillus cereus B4264 chromosome, complete genomeUvrD/Rep family helicase4e-44180
NC_013406:4023367:4037035403703540394612427Paenibacillus sp. Y412MC10 chromosome, complete genomeUvrD/Rep family helicase5e-44179
NC_015978:352478:3729943729943752942301Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completehypothetical protein5e-44179
NC_003909:1139556:1140312114031211418891578Bacillus cereus ATCC 10987, complete genome6e-44179
NC_013199:1966334:1984402198440219866932292Lactobacillus rhamnosus Lc 705, complete genomesuperfamily I DNA and RNA helicase-like protein8e-43176
NC_015975:441580:4644374644374667162280Lactobacillus ruminis ATCC 27782 chromosome, complete genomeATP-dependent DNA helicase7e-42172
NC_015275:3407358:3444146344414634464312286Clostridium lentocellum DSM 5427 chromosome, complete genomeUvrD/REP helicase2e-39164
NC_015977:3424178:3522058352205835252703213Roseburia hominis A2-183 chromosome, complete genomeUvrD/Rep helicase family protein4e-37157
NC_003909:1139556:113955611395561140365810Bacillus cereus ATCC 10987, complete genomehypothetical protein3e-28127
NC_013947:1296877:1296877129687712988141938Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeSuperfamily I DNA and RNA helicase-like protein2e-27124
NC_009342:1570000:1585112158511215874632352Corynebacterium glutamicum R chromosome, complete genomehypothetical protein3e-27124
NC_012803:1552122:1568191156819115704672277Micrococcus luteus NCTC 2665, complete genomeDNA/RNA helicase, superfamily I3e-27124
NC_016582:10287865:1030133210301332103034102079Streptomyces bingchenggensis BCW-1 chromosome, complete genomesuperfamily I DNA and RNA helicase-like protein6e-26119
NC_004369:1552847:1568036156803615703812346Corynebacterium efficiens YS-314, complete genomehypothetical protein4e-25117
NC_016582:7946000:7960285796028579624622178Streptomyces bingchenggensis BCW-1 chromosome, complete genomesuperfamily I DNA and RNA helicase-like protein5e-25116
NC_013729:380312:3803123803123824802169Kribbella flavida DSM 17836, complete genomeSuperfamily I DNA and RNA helicase-like protein5e-25116
NC_016113:11500:1173611736137632028Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequenceATP-dependent DNA helicase1e-24115
NC_006361:4574536:4576673457667345788532181Nocardia farcinica IFM 10152, complete genomeputative helicase1e-24115
NC_013757:1888850:1891505189150518936552151Geodermatophilus obscurus DSM 43160, complete genomesuperfamily I DNA and RNA helicase5e-23110
NC_018524:4988810:5009665500966550118152151Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomeuvrD/REP helicase N-terminal domain protein4e-21103
NC_014210:3170537:3190003319000331931493147Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,Superfamily I DNA and RNA helicase2e-1481.3
NC_009973:301391:3101723101723123402169Herpetosiphon aurantiacus ATCC 23779 plasmid pHAU01, completesuperfamily I DNA/RNA helicase8e-1479.7
NC_017093:7234589:7240800724080072424881689Actinoplanes missouriensis 431, complete genomehypothetical protein5e-1170.5
NC_012918:1814000:1826660182666018285491890Geobacter sp. M21 chromosome, complete genomesuperfamily I DNA and RNA helicase-like protein2e-1068.2
NC_007498:3399478:3401690340169034036661977Pelobacter carbinolicus DSM 2380, complete genomehypothetical protein2e-1068.2
NC_013510:2937530:2960722296072229633072586Thermomonospora curvata DSM 43183, complete genomeSuperfamily I DNA and RNA helicase-like protein5e-0963.5
NC_008060:3155133:3199939319993932020262088Burkholderia cenocepacia AU 1054 chromosome 1, complete sequenceUvrD/REP helicase4e-0757.4
NC_008781:330919:3478083478083499372130Polaromonas naphthalenivorans CJ2, complete genomeUvrD/REP helicase4e-0757
NC_017511:852260:8522608522608542752016Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomeputative ATP-dependent DNA helicase5e-0757
NC_011035:933269:9352999352999373142016Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeputative ATP-dependent DNA helicase5e-0757
NC_008767:1363288:1380391138039113824632073Neisseria meningitidis FAM18, complete genomeATP-dependent DNA helicase7e-0756.6
NC_007434:111607:1258451258451280462202Burkholderia pseudomallei 1710b chromosome I, complete sequenceATP-dependent DNA helicase Rep2e-0655.1
NC_009074:3791232:3815754381575438178412088Burkholderia pseudomallei 668 chromosome I, complete sequenceATP-dependent DNA helicase Rep2e-0655.1
NC_009076:3876733:3891166389116638932532088Burkholderia pseudomallei 1106a chromosome I, complete sequenceATP-dependent DNA helicase Rep2e-0655.1
NC_006350:3957454:3977437397743739795242088Burkholderia pseudomallei K96243 chromosome 1, complete sequenceATP-dependent DNA helicase Rep2e-0655.1
NC_009256:176403:1774401774401795272088Burkholderia vietnamiensis G4 chromosome 1, complete sequenceUvrD/REP helicase2e-0655.1
NC_007651:3719191:3719191371919137217372547Burkholderia thailandensis E264 chromosome I, complete sequenceATP-dependent DNA helicase Rep2e-0654.7
NC_007347:3612918:3635779363577936378932115Ralstonia eutropha JMP134 chromosome 1, complete sequenceUvrD/REP helicase3e-0654.7
NC_007645:713930:7350657350657372302166Hahella chejuensis KCTC 2396, complete genomeSuperfamily I DNA and RNA helicase3e-0654.7
NC_014550:615609:6289646289646313422379Arthrobacter arilaitensis Re117, complete genomeATP-dependent DNA helicase PcrA3e-0654.3
NC_002505:168532:1942141942141963852172Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, completeDNA helicase II6e-0653.5
NC_012668:442601:4426014426014447722172Vibrio cholerae MJ-1236 chromosome 1, complete sequenceDNA-dependent helicase II6e-0653.5
NC_016445:2593800:2619482261948226216532172Vibrio cholerae O1 str. 2010EL-1786 chromosome 1, completeDNA-dependent helicase II6e-0653.5
NC_016944:168530:1942241942241963952172Vibrio cholerae IEC224 chromosome I, complete sequenceDNA-dependent helicase II6e-0653.5
NC_018867:10238:5577655776576231848Dehalobacter sp. CF chromosome, complete genomeATP-dependent DNA helicase UvrD/PcrA6e-0653.1
NC_012034:6469:3152031520339792460Anaerocellum thermophilum DSM 6725, complete genomeLexA repressor6e-0653.1
NC_007645:5801295:5826907582690758282711365Hahella chejuensis KCTC 2396, complete genomeSuperfamily I DNA and RNA helicase7e-0653.1