Pre_GI: BLASTP Hits

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Query: NC_004557:2078000:2093943 Clostridium tetani E88, complete genome

Start: 2093943, End: 2094521, Length: 579

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010320:671699:671699671699672277579Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein2e-49194
NC_009922:2323083:233865723386572339232576Alkaliphilus oremlandii OhILAs, complete genomeprotein of unknown function DUF2183e-30131
NC_013093:3768790:3774980377498037759901011Actinosynnema mirum DSM 43827, complete genomeprotein of unknown function DUF2184e-22104
NC_013714:570329:5839885839885850281041Bifidobacterium dentium Bd1, complete genomehypothetical protein8e-21100
NC_013204:74855:9231892318933191002Eggerthella lenta DSM 2243, complete genomeprotein of unknown function DUF2181e-2099.4
NC_011898:2951670:297338729733872974157771Clostridium cellulolyticum H10, complete genomeprotein of unknown function DUF2181e-2099.4
NC_008262:904000:919919919919920539621Clostridium perfringens SM101, complete genomehypothetical protein2e-2099
NC_003366:981105:993161993161993781621Clostridium perfringens str. 13, complete genomehypothetical protein3e-2098.2
NC_015519:426948:427793427793428374582Tepidanaerobacter sp. Re1 chromosome, complete genomehypothetical protein2e-1995.5
NC_018720:417500:4306074306074316891083Bifidobacterium asteroides PRL2011 chromosome, complete genomehypothetical protein3e-1995.1
NC_016943:1560000:156006015600601560683624Blastococcus saxobsidens DD2, complete genomehypothetical protein5e-1994
NC_015136:1:139571395714517561Burkholderia sp. CCGE1001 chromosome 1, complete sequencehypothetical protein1e-1892.8
NC_018750:3661243:3680081368008136811031023Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein1e-1892.8
NC_015683:2279904:2285743228574322867681026Corynebacterium ulcerans BR-AD22 chromosome, complete genomehypothetical protein2e-1892
NC_017317:2181284:2186457218645721874821026Corynebacterium ulcerans 809 chromosome, complete genomehypothetical protein2e-1891.7
NC_016641:4290350:430648543064854307180696Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein7e-1890.1
NC_013406:7024149:704294670429467043530585Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein3e-1788.2
NC_013316:2033906:203736120373612038107747Clostridium difficile R20291, complete genomehypothetical protein3e-1788.2
NC_016887:1714664:171537617153761715996621Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein4e-1787.4
NC_010515:2449143:247141524714152472107693Burkholderia cenocepacia MC0-3 chromosome 2, complete sequenceprotein of unknown function DUF2185e-1787.4
NC_011725:2949519:296654729665472967179633Bacillus cereus B4264 chromosome, complete genomehypothetical protein8e-1786.7
NC_003366:1427785:144903014490301449803774Clostridium perfringens str. 13, complete genomehypothetical protein3e-1684.7
NC_008618:1206157:122090612209061221658753Bifidobacterium adolescentis ATCC 15703, complete genomehypothetical protein3e-1684.7
NC_017511:1812000:183392418339241834580657Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein6e-1683.6
NC_011035:1908000:193008119300811930737657Neisseria gonorrhoeae NCCP11945 chromosome, complete genomePeriplasmic protein6e-1683.6
NC_015913:1117500:112210211221021122650549Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomehypothetical protein1e-1582.8
NC_017294:1096000:110045111004511100999549Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomemembrane protein1e-1582.8
NC_017353:646195:6461956461956471991005Staphylococcus lugdunensis N920143, complete genomeputative lantibiotic resistance protein4e-1581.3
NC_013714:1521404:153780115378011538427627Bifidobacterium dentium Bd1, complete genomehypothetical protein5e-1580.9
NC_020207:843822:8689528689528701511200Enterococcus faecium NRRL B-2354, complete genomehypothetical protein6e-1580.5
NC_010718:2265447:229395322939532294537585Natranaerobius thermophilus JW/NM-WN-LF, complete genomeprotein of unknown function DUF2186e-1580.5
NC_015737:2691246:273595527359552736701747Clostridium sp. SY8519, complete genomehypothetical protein8e-1580.1
NC_017295:389500:406780406780407457678Clostridium acetobutylicum EA 2018 chromosome, complete genomehypothetical protein4e-1477.8
NC_003030:389500:406790406790407467678Clostridium acetobutylicum ATCC 824, complete genomeUncharacterized conserved membrane protein, SANA family4e-1477.8
NC_015687:389500:406786406786407463678Clostridium acetobutylicum DSM 1731 chromosome, complete genomehypothetical protein4e-1477.8
NC_016012:1010405:101752610175261018074549Candidatus Arthromitus sp. SFB-rat-Yit, complete genomemembrane protein1e-1376.6
NC_013947:4979000:498271749827174983394678Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehypothetical protein3e-1375.1
NC_014758:245707:255619255619256335717Calditerrivibrio nitroreducens DSM 19672 chromosome, completehypothetical protein2e-1272
NC_015711:3122000:314455331445533145134582Myxococcus fulvus HW-1 chromosome, complete genomehypothetical protein3e-1271.2
NC_015275:3846260:386769438676943868395702Clostridium lentocellum DSM 5427 chromosome, complete genomeprotein of unknown function DUF2185e-1167.4
NC_007969:2885249:291607429160742916853780Psychrobacter cryohalolentis K5, complete genomeprotein of unknown function DUF2184e-1064.3
NC_014033:164670:1747771747771761201344Prevotella ruminicola 23 chromosome, complete genomehypothetical protein3e-0961.6
NC_012225:1213421:122800812280081228829822Brachyspira hyodysenteriae WA1, complete genomehypothetical protein9e-0960.1
NC_014168:994640:99966599966510006991035Segniliparus rotundus DSM 44985 chromosome, complete genomehypothetical protein1e-0859.7
NC_017243:2383577:239709623970962397917822Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein6e-0857
NC_014150:2501299:251841425184142519220807Brachyspira murdochii DSM 12563 chromosome, complete genomeprotein of unknown function DUF2187e-0857
NC_008570:546736:5467365467365477611026Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomesanA protein3e-0754.7
NC_013440:3658000:365820536582053658804600Haliangium ochraceum DSM 14365, complete genomeprotein of unknown function DUF2185e-0754.3
NC_010842:2310756:232473823247382325415678Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)' chromosomehypothetical protein1e-0653.1
NC_010602:2244729:231935223193522320029678Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'hypothetical protein1e-0653.1
NC_012563:811993:811993811993812661669Clostridium botulinum A2 str. Kyoto, complete genomeputative SanA protein1e-0653.1
NC_010159:1818500:1834856183485618359831128Yersinia pestis Angola, complete genomehypothetical protein2e-0652.4
NC_010634:2894631:2931998293199829331251128Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-0652.4
NC_006155:2979500:3014057301405730151841128Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-0652.4
NC_003143:2804500:2820818282081828219451128Yersinia pestis CO92, complete genomehypothetical protein2e-0652.4
NC_010376:186510:231558231558232484927Finegoldia magna ATCC 29328, complete genomehypothetical protein2e-0652.4
NC_008149:2366500:2382602238260223837291128Yersinia pestis Nepal516, complete genomehypothetical protein2e-0652.4
NC_005810:2549680:2586872258687225879991128Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-0652.4
NC_009381:2138625:2173026217302621741531128Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-0652.4
NC_009708:1735903:1737907173790717390341128Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein2e-0652.4
NC_014029:2756500:2773141277314127742681128Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-0652.4
NC_017154:2804000:2820291282029128214181128Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-0652.4
NC_017160:2787637:2787637278763727887641128Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-0652.4
NC_017265:1571305:1571305157130515724321128Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-0652.4
NC_014507:906960:909532909532910080549Methanoplanus petrolearius DSM 11571 chromosome, complete genomehypothetical protein3e-0652
NC_010655:2065567:207210520721052072758654Akkermansia muciniphila ATCC BAA-835, complete genomeprotein of unknown function DUF2182e-0652
NC_013456:1743046:175612017561201756737618Vibrio sp. Ex25 chromosome 1, complete genomehypothetical protein5e-0650.8
NC_020125:1237536:125427912542791254890612Riemerella anatipestifer RA-CH-2, complete genomehypothetical protein8e-0650.4
NC_017045:631761:635472635472636044573Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,8e-0650.1
NC_014738:469945:473656473656474228573Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,hypothetical protein8e-0650.1