Pre_GI: BLASTP Hits

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Query: NC_004557:1553000:1566902 Clostridium tetani E88, complete genome

Start: 1566902, End: 1568017, Length: 1116

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009633:3933941:3953312395331239544451134Alkaliphilus metalliredigens QYMF chromosome, complete genomemembrane spanning protein5e-116417
NC_009922:2556033:2578350257835025794441095Alkaliphilus oremlandii OhILAs, complete genomeconserved hypothetical protein2e-121435
NC_009697:2173000:2189422218942221905341113Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein2e-177622
NC_009495:2244774:2260780226078022618921113Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein2e-177622
NC_009698:2171151:2189641218964121907531113Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein2e-177622
NC_010674:1496500:1499637149963715007341098Clostridium botulinum B str. Eklund 17B, complete genomemembrane spanning protein8e-133473
NC_012658:2295536:2318150231815023192621113Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein4e-178624
NC_010723:1465097:1469850146985014709471098Clostridium botulinum E3 str. Alaska E43, complete genomemembrane spanning protein2e-132472
NC_017297:2288000:2310115231011523112271113Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein1e-177622
NC_009699:2287893:2309999230999923111111113Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein1e-177622
NC_014328:4316008:4337882433788243389641083Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein3e-104378
NC_014328:4316008:4336342433634243374301089Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein4e-139494
NC_008593:1103293:110531811053181106262945Clostridium novyi NT, complete genomelicB protein , putative2e-0653.9
NC_010001:1745089:1751974175197417529901017Clostridium phytofermentans ISDg, complete genomemembrane spanning protein4e-44179
NC_011883:2826000:2830036283003628310641029Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774,protein of unknown function DUF6 transmembrane2e-1997.1
NC_013204:2826500:2852123285212328532321110Eggerthella lenta DSM 2243, complete genomehypothetical protein9e-75280
NC_003454:1889529:189260218926021893570969Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeCholine transport protein2e-1273.6
NC_014363:645397:674033674033674983951Olsenella uli DSM 7084 chromosome, complete genomeprotein of unknown function DUF6 transmembrane1e-1377.8