Pre_GI: BLASTN Hits

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Query: NC_003997:674265 Bacillus anthracis str. Ames, complete genome

Start: 674265, End: 693149, Length: 18885

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007530:67426567426569315018886Bacillus anthracis str. 'Ames Ancestor', complete genome029520BLASTN svgBLASTP svg
NC_005945:67433767433769304518709Bacillus anthracis str. Sterne, complete genome022070BLASTN svgBLASTP svg
UCMB5137:28945112894511291649621986Bacillus atrophaeus UCMB-51371e-1075.8BLASTN svgBLASTP svg
NC_014829:133305*13330517500741703Bacillus cellulosilyticus DSM 2522 chromosome, complete genome1e-20109BLASTN svgBLASTP svg
NC_004722:65095065095066943618487Bacillus cereus ATCC 14579, complete genome015180BLASTN svgBLASTP svg
NC_006274:65992265992268275922838Bacillus cereus E33L, complete genome027480BLASTN svgBLASTP svg
NC_011772:64777864777866815320376Bacillus cereus G9842, complete genome015090BLASTN svgBLASTP svg
NC_009848:16137316137318435122979Bacillus pumilus SAFR-032, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_005957:66795466795469053422581Bacillus thuringiensis serovar konkukian str. 97-27, complete022810BLASTN svgBLASTP svg
NC_010184:66122666122668503723812Bacillus weihenstephanensis KBAB4, complete genome015730BLASTN svgBLASTP svg
NC_014614:862138621310565919447Clostridium sticklandii, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_011661:1175743*1175743119876723025Dictyoglomus turgidum DSM 6724, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_015703:75417275417278042826257Runella slithyformis DSM 19594 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014538:187747*18774720633818592Thermoanaerobacter sp. X513 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg