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Query: NC_003155:2730469 Streptomyces avermitilis MA-4680, complete genome

Start: 2730469, End: 2750248, Length: 19780

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_018750:63158026315802633862022819Streptomyces venezuelae ATCC 10712, complete genome02438BLASTN svgBLASTP svg
NC_021177:66626686662668668358820921Streptomyces fulvissimus DSM 40593, complete genome02163BLASTN svgBLASTP svg
NC_015953:59084675908467592977521309Streptomyces sp. SirexAA-E chromosome, complete genome02135BLASTN svgBLASTP svg
NC_010572:17486681748668176920720540Streptomyces griseus subsp. griseus NBRC 13350, complete genome02006BLASTN svgBLASTP svg
NC_003888:65680006568000659069022691Streptomyces coelicolor A3(2), complete genome01957BLASTN svgBLASTP svg
NC_019673:8161242*8161242818734226101Saccharothrix espanaensis DSM 44229 complete genome3e-70274BLASTN svgBLASTP svg
NC_003888:40312994031299405409922801Streptomyces coelicolor A3(2), complete genome4e-51210BLASTN svgBLASTP svg
NC_013131:7401253*7401253742304021788Catenulispora acidiphila DSM 44928, complete genome2e-25125BLASTN svgBLASTP svg
NC_013947:3080290*3080290311039130102Stackebrandtia nassauensis DSM 44728 chromosome, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_019673:67784016778401680115922759Saccharothrix espanaensis DSM 44229 complete genome2e-1385.7BLASTN svgBLASTP svg
NC_014761:1981435*1981435200568024246Oceanithermus profundus DSM 14977 chromosome, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_013947:2113941*2113941214484730907Stackebrandtia nassauensis DSM 44728 chromosome, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_019673:80579418057941808196224022Saccharothrix espanaensis DSM 44229 complete genome1e-1179.8BLASTN svgBLASTP svg
NC_013521:16193941619394164259923206Sanguibacter keddieii DSM 10542, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_013739:5705325*5705325573909933775Conexibacter woesei DSM 14684, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_010572:18850018850021341824919Streptomyces griseus subsp. griseus NBRC 13350, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_014210:41884484188448421709828651Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,4e-0867.9BLASTN svgBLASTP svg
NC_013715:1376985*1376985140051523531Rothia mucilaginosa DY-18, complete genome2e-0661.9BLASTN svgBLASTP svg