Pre_GI: BLASTP Hits

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Query: NC_003155:6295078:6304532 Streptomyces avermitilis MA-4680, complete genome

Start: 6304532, End: 6305194, Length: 663

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016582:6999074:701240870124087013058651Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein1e-59229
NC_003888:3111998:312134431213443121892549Streptomyces coelicolor A3(2), complete genomehypothetical protein1e-40166
NC_015957:336500:344967344967345599633Streptomyces violaceusniger Tu 4113 chromosome, complete genomehypothetical protein3e-33141
NC_013929:6343000:635622163562216356853633Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein9e-29126
NC_016111:3577572:358579435857943586369576Streptomyces cattleya NRRL 8057, complete genomeregulatory protein2e-25115
NC_010572:5445081:547466554746655474991327Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein2e-1685.9
NC_003155:210240:2228712228712246911821Streptomyces avermitilis MA-4680, complete genomehypothetical protein3e-1478.6
NC_016109:5290000:5311921531192153146922772Kitasatospora setae KM-6054, complete genomeputative protein kinase/phosphatase4e-1168.2
NC_016109:4581467:459704245970424597479438Kitasatospora setae KM-6054, complete genomehypothetical protein4e-1168.2
NC_015953:5444572:5460375546037554629992625Streptomyces sp. SirexAA-E chromosome, complete genomeputative PAS/PAC sensor protein5e-1167.8
NC_016109:5290000:5314849531484953173112463Kitasatospora setae KM-6054, complete genomeputative protein kinase/phosphatase7e-1167.4
NC_014165:2888961:290422029042202904699480Thermobispora bispora DSM 43833 chromosome, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase1e-1066.6
NC_018750:5828000:5841875584187558445202646Streptomyces venezuelae ATCC 10712, complete genomeregulatory protein2e-1066.2
NC_015957:115133:1151331151331177992667Streptomyces violaceusniger Tu 4113 chromosome, complete genomesignal transduction histidine kinase regulating citrate/malate metabolism2e-1065.9
NC_003155:921494:9359539359539387272775Streptomyces avermitilis MA-4680, complete genomemagnesium or manganese-dependent protein phosphatase2e-1065.9
NC_018750:6588206:660790366079036608355453Streptomyces venezuelae ATCC 10712, complete genomeprobable regulatory protein4e-1064.7
NC_018750:3859127:3872413387241338745302118Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein6e-1064.3
NC_016582:10015558:1002419110024191100262512061Streptomyces bingchenggensis BCW-1 chromosome, complete genomemagnesium or manganese-dependent protein phosphatase8e-1063.9
NC_013929:3299736:334538933453893345784396Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein3e-0962
NC_003888:4927170:496064949606494961074426Streptomyces coelicolor A3(2), complete genomehypothetical protein9e-0960.5
NC_013929:5431954:543593854359385436402465Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein2e-0859.7
NC_016114:907500:922845922845923339495Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeATP-binding region ATPase domain-containing protein3e-0858.5
NC_013929:3600343:362454136245413624975435Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein4e-0858.2
NC_016111:3659269:367122436712243671643420Streptomyces cattleya NRRL 8057, complete genomehypothetical protein4e-0858.2
NC_013510:170199:176061176061176585525Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase5e-0857.8
NC_003888:7706226:771280577128057713266462Streptomyces coelicolor A3(2), complete genomehypothetical protein7e-0857.4
NC_015957:7249873:726567072656707266197528Streptomyces violaceusniger Tu 4113 chromosome, complete genome9e-0857
NC_016111:1546505:156117815611781561573396Streptomyces cattleya NRRL 8057, complete genomeRegulatory protein (fragment)1e-0757
NC_014210:618500:635276635276635773498Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,putative signal transduction histidine kinase2e-0756.2
NC_007333:3244572:325636332563633256776414Thermobifida fusca YX, complete genomehypothetical protein2e-0755.8
NC_007777:1018824:103468310346831035270588Frankia sp. CcI3, complete genomehypothetical protein4e-0755.1
NC_013595:8603188:862337686233768623834459Streptosporangium roseum DSM 43021, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase4e-0754.7
NC_003888:4613000:462299346229934623433441Streptomyces coelicolor A3(2), complete genomeAbaA-like regulatory protein5e-0754.7
NC_016111:4003290:401778740177874018248462Streptomyces cattleya NRRL 8057, complete genomehypothetical protein5e-0754.7
NC_003155:5005913:500675050067505007181432Streptomyces avermitilis MA-4680, complete genomeregulatory protein5e-0754.7
NC_013929:3299736:332127133212713321879609Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein6e-0754.3
NC_014165:27246:454424544245897456Thermobispora bispora DSM 43833 chromosome, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase6e-0754.3
NC_016582:1639375:1662621166262116654342814Streptomyces bingchenggensis BCW-1 chromosome, complete genomeputative regulatory protein phosphatase6e-0754.3
NC_016113:887582:896879896879897598720Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequencehypothetical protein8e-0753.9
NC_013510:3065000:3084646308464630867122067Thermomonospora curvata DSM 43183, complete genomeprotein serine phosphatase with GAF(s) sensor(s)1e-0653.5
NC_016111:4613599:462047546204754620912438Streptomyces cattleya NRRL 8057, complete genomeregulatory protein (fragment)1e-0653.1
NC_010572:4585500:4587521458752145893051785Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein2e-0653.1
NC_015953:3313000:332619333261933326627435Streptomyces sp. SirexAA-E chromosome, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase2e-0652.8
NC_013510:2432879:244682024468202447224405Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase2e-0652.4
NC_016582:9551123:955554795555479555966420Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein4e-0651.6
NC_003888:7337453:735676673567667357356591Streptomyces coelicolor A3(2), complete genomehypothetical protein5e-0651.2
NC_016109:5768000:580196058019605802550591Kitasatospora setae KM-6054, complete genomehypothetical protein7e-0650.8
NC_013595:9651019:966629696662969666874579Streptosporangium roseum DSM 43021, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase9e-0650.4
NC_013093:2547608:255503225550322555436405Actinosynnema mirum DSM 43827, complete genomehypothetical protein9e-0650.4