Pre_GI: BLASTP Hits

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Query: NC_003155:6295078:6301736 Streptomyces avermitilis MA-4680, complete genome

Start: 6301736, End: 6302587, Length: 852

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013929:1799594:182023918202391821093855Streptomyces scabiei 87.22 chromosome, complete genomeregulatory protein9e-72270
NC_016109:4753493:476778247677824768546765Kitasatospora setae KM-6054, complete genomehypothetical protein4e-71268
NC_003903:167825:178957178957179805849Streptomyces coelicolor A3(2) plasmid SCP1, complete sequencehypothetical protein1e-68259
NC_016109:4455158:446682644668264467680855Kitasatospora setae KM-6054, complete genomeputative transcriptional regulator6e-68257
NC_003888:3111998:312441731244173125262846Streptomyces coelicolor A3(2), complete genomeregulatory protein8e-65247
NC_013929:6343000:635192363519236352771849Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein9e-65246
NC_016109:6640000:664741066474106648264855Kitasatospora setae KM-6054, complete genomeputative transcriptional regulator4e-63241
NC_018524:301992:314254314254315090837Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomehelix-turn-helix family protein1e-54213
NC_013510:465188:482165482165483013849Thermomonospora curvata DSM 43183, complete genometranscriptional regulator, XRE family8e-51200
NC_016887:1093609:110105311010531101895843Nocardia cyriacigeorgica GUH-2, complete genomeputative DNA-binding protein1e-48193
NC_010572:1:444144415283843Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative DNA-binding protein2e-41169
NC_010572:8493946:854064785406478541489843Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative DNA-binding protein2e-41169
NC_010572:8493946:444144415283843Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative DNA-binding protein2e-41169
NC_006361:4098469:410594941059494106791843Nocardia farcinica IFM 10152, complete genomeputative DNA-binding protein4e-38158
NC_010572:5445081:547300054730005473845846Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative DNA-binding protein2e-31136
NC_021177:6127431:613261361326136133464852Streptomyces fulvissimus DSM 40593, complete genomeTranscriptional regulator2e-28126
NC_021177:2766910:277838827783882779236849Streptomyces fulvissimus DSM 40593, complete genomePutative DNA-binding protein2e-28125
NC_016111:5515462:552138055213805521865486Streptomyces cattleya NRRL 8057, complete genomeHelix-turn-helix protein (fragment)3e-26119
NC_008278:6885254:690516169051616905994834Frankia alni ACN14a, complete genomePutative protein; Putative regulatory protein3e-24112
NC_016109:7445603:745160774516077452446840Kitasatospora setae KM-6054, complete genomeputative transcriptional regulator8e-23107
NC_013929:3299736:334588333458833346713831Streptomyces scabiei 87.22 chromosome, complete genomeregulatory protein2e-20100
NC_013595:8338619:834680983468098347672864Streptosporangium roseum DSM 43021, complete genomehypothetical protein4e-2099
NC_018524:2246225:225320822532082254032825Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomehelix-turn-helix family protein2e-1996.3
NC_016111:1546505:155441115544111555241831Streptomyces cattleya NRRL 8057, complete genomehypothetical protein5e-1788.6
NC_016582:3763476:377266637726663773532867Streptomyces bingchenggensis BCW-1 chromosome, complete genomeputative DNA-binding protein6e-1684.7
NC_016582:6999074:701136370113637012175813Streptomyces bingchenggensis BCW-1 chromosome, complete genomeDNA-binding protein2e-1583.6
NC_017186:7841740:785295378529537853720768Amycolatopsis mediterranei S699 chromosome, complete genomehypothetical protein6e-1581.6
NC_014318:7821227:785290778529077853674768Amycolatopsis mediterranei U32 chromosome, complete genomehelix-turn-helix domain-containing protein6e-1581.6
NC_013510:5309143:531986853198685320725858Thermomonospora curvata DSM 43183, complete genomehelix-turn-helix domain protein3e-1479.3
NC_013510:5115500:513205451320545132719666Thermomonospora curvata DSM 43183, complete genomehypothetical protein3e-1376.3
NC_014210:5309121:532623653262365327090855Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, XRE family4e-1375.5
NC_003155:6295078:630347763034776304325849Streptomyces avermitilis MA-4680, complete genomeDNA-binding protein5e-1375.1
NC_013595:8603188:862421786242178625092876Streptosporangium roseum DSM 43021, complete genomeputative transcriptional regulator, XRE family1e-1273.6
NC_014210:5048502:506004750600475060913867Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, XRE family2e-1272.8
NC_018750:6950695:697001969700196970894876Streptomyces venezuelae ATCC 10712, complete genomeputative DNA-binding protein3e-1272.4
NC_018524:301992:313568313568314176609Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomeputative dNA-binding protein8e-1271.2
NC_007333:430000:437708437708438553846Thermobifida fusca YX, complete genomehelix-turn-helix motif1e-1170.1
NC_009380:581000:589581589581590393813Salinispora tropica CNB-440 chromosome, complete genomehelix-turn-helix domain-containing protein2e-1169.7
NC_013929:7663631:766986276698627670857996Streptomyces scabiei 87.22 chromosome, complete genomeDNA-binding protein6e-1168.2
NC_014165:2888961:290308629030862903943858Thermobispora bispora DSM 43833 chromosome, complete genomehelix-turn-helix domain-containing protein6e-1168.2
NC_021177:2309615:232354323235432324382840Streptomyces fulvissimus DSM 40593, complete genomeTranscriptional regulator, XRE family6e-1168.2
NC_014210:1588426:159930915993091600181873Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,helix-turn-helix domain protein9e-1167.8
NC_008278:6885254:690729269072926908092801Frankia alni ACN14a, complete genomeputative DNA-binding protein1e-1067
NC_009380:725870:725870725870726763894Salinispora tropica CNB-440 chromosome, complete genomehelix-turn-helix domain-containing protein2e-1066.6
NC_013595:8553904:856230685623068562959654Streptosporangium roseum DSM 43021, complete genomehypothetical protein2e-1066.6
NC_007333:2093167:210360821036082104447840Thermobifida fusca YX, complete genomehelix-turn-helix motif2e-1066.2
NC_007777:461500:470552470552471442891Frankia sp. CcI3, complete genomeputative DNA-binding protein2e-1066.2
NC_013093:7174636:717771371777137178570858Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, XRE family4e-1065.5
NC_013510:3117837:314071431407143141526813Thermomonospora curvata DSM 43183, complete genometranscriptional regulator, XRE family6e-1064.7
NC_007333:1129826:114288611428861143740855Thermobifida fusca YX, complete genomehelix-turn-helix motif8e-1064.3
NC_015434:4640769:464580646458064646765960Verrucosispora maris AB-18-032 chromosome, complete genomehelix-turn-helix domain-containing protein9e-1064.3
NC_018524:2246225:227205122720512272884834Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomehelix-turn-helix family protein1e-0963.9
NC_015953:3313000:332751533275153328384870Streptomyces sp. SirexAA-E chromosome, complete genomeXRE family transcriptional regulator1e-0963.9
NC_009380:4184695:419105441910544191791738Salinispora tropica CNB-440 chromosome, complete genomehypothetical protein1e-0963.9
NC_013510:2288746:229930422993042300185882Thermomonospora curvata DSM 43183, complete genomehelix-turn-helix domain protein2e-0963.5
NC_015957:336500:343902343902344747846Streptomyces violaceusniger Tu 4113 chromosome, complete genomehelix-turn-helix domain-containing protein2e-0963.2
NC_016582:9551123:955614895561489556957810Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein2e-0963.2
NC_009953:1034809:104109910410991041896798Salinispora arenicola CNS-205 chromosome, complete genomehelix-turn-helix domain-containing protein2e-0962.8
NC_013947:4695000:470870947087094709560852Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehelix-turn-helix domain-containing protein4e-0962.4
NC_003888:3111998:312209131220913122933843Streptomyces coelicolor A3(2), complete genomeregulatory protein4e-0962.4
NC_014666:8198554:822022582202258221091867Frankia sp. EuI1c chromosome, complete genomehelix-turn-helix domain protein4e-0962
NC_017093:8518961:852462485246248525514891Actinoplanes missouriensis 431, complete genomeputative DNA-binding protein6e-0961.6
NC_013510:1637730:164894816489481649778831Thermomonospora curvata DSM 43183, complete genometranscriptional regulator, XRE family7e-0961.2
NC_014666:1117000:113569311356931136553861Frankia sp. EuI1c chromosome, complete genomehelix-turn-helix domain protein7e-0961.2
NC_009380:1491428:151443915144391515320882Salinispora tropica CNB-440 chromosome, complete genomehypothetical protein8e-0961.2
NC_015434:3755560:376664437666443767525882Verrucosispora maris AB-18-032 chromosome, complete genomehelix-turn-helix domain-containing protein1e-0860.8
NC_018750:6192970:620089562008956201815921Streptomyces venezuelae ATCC 10712, complete genomeregulatory protein1e-0860.5
NC_016582:4934854:494431449443144945195882Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein2e-0860.1
NC_013929:6526745:653513365351336535969837Streptomyces scabiei 87.22 chromosome, complete genomeDNA-binding protein2e-0860.1
NC_013929:7278414:728707572870757287953879Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein2e-0860.1
NC_016111:5515462:552035955203595521216858Streptomyces cattleya NRRL 8057, complete genomeDNA-binding protein2e-0860.1
NC_016113:1143580:115353911535391154375837Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequenceDNA-binding protein3e-0859.3
NC_008278:132000:141420141420142196777Frankia alni ACN14a, complete genomePutative DNA-binding protein3e-0858.9
NC_006361:498305:508199508199509092894Nocardia farcinica IFM 10152, complete genomeputative DNA-binding protein4e-0858.9
NC_016111:3577572:358466335846633585508846Streptomyces cattleya NRRL 8057, complete genomeregulatory protein4e-0858.9
NC_010572:1872840:188568418856841886526843Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative DNA-binding protein4e-0858.9
NC_013929:6343000:635516563551656355971807Streptomyces scabiei 87.22 chromosome, complete genomeregulatory protein5e-0858.5
NC_018681:2176000:218106721810672181957891Nocardia brasiliensis ATCC 700358 chromosome, complete genomeXRE family transcriptional regulator5e-0858.5
NC_007333:1559321:156710515671051568004900Thermobifida fusca YX, complete genomeputative DNA-binding protein8e-0857.8
NC_014210:618500:636013636013636870858Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,helix-turn-helix domain protein8e-0857.8
NC_013510:465188:475826475826476707882Thermomonospora curvata DSM 43183, complete genometranscriptional regulator, XRE family1e-0757.4
NC_013510:1614000:161614016161401616946807Thermomonospora curvata DSM 43183, complete genometranscriptional regulator, XRE family2e-0757
NC_016887:1949927:196913919691391969894756Nocardia cyriacigeorgica GUH-2, complete genomeXRE family transcriptional regulator2e-0757
NC_014210:1588426:160049716004971601357861Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, XRE family2e-0757
NC_016114:907500:914418914418915302885Streptomyces flavogriseus ATCC 33331 chromosome, complete genomehelix-turn-helix domain-containing protein2e-0756.6
NC_014210:2277971:228780622878062288609804Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, XRE family2e-0756.6
NC_016887:4403872:441600344160034416932930Nocardia cyriacigeorgica GUH-2, complete genomeputative DNA binding protein3e-0755.8
NC_013510:2937530:294657529465752947384810Thermomonospora curvata DSM 43183, complete genometranscriptional regulator, XRE family8e-0754.7
NC_013947:1537275:155630815563081557171864Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehypothetical protein8e-0754.7
NC_016111:4003290:401923940192394020021783Streptomyces cattleya NRRL 8057, complete genomeDNA-binding protein9e-0754.3
NC_013159:1225866:123908512390851239939855Saccharomonospora viridis DSM 43017, complete genomepredicted transcription factor, MBF1 like protein1e-0653.9
NC_003888:7337453:735751973575197358352834Streptomyces coelicolor A3(2), complete genomehypothetical protein2e-0653.1
NC_009142:949510:967187967187968044858Saccharopolyspora erythraea NRRL 2338, complete genometranscriptional regulator, XRE family3e-0652.8
NC_016582:6509792:652268365226836523435753Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein4e-0652
NC_003888:4927170:495958449595844960435852Streptomyces coelicolor A3(2), complete genomehypothetical protein6e-0651.6