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Query: NC_003155:6295078:6301177 Streptomyces avermitilis MA-4680, complete genome

Start: 6301177, End: 6301710, Length: 534

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016109:4753493:476714647671464767670525Kitasatospora setae KM-6054, complete genomehypothetical protein4e-63240
NC_003903:167825:178395178395178949555Streptomyces coelicolor A3(2) plasmid SCP1, complete sequencehypothetical protein2e-51201
NC_013929:6343000:635278863527886353318531Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein6e-47186
NC_016109:6640000:664830166483016648822522Kitasatospora setae KM-6054, complete genomehypothetical protein8e-42169
NC_013929:1799594:182110018211001821615516Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein1e-38159
NC_003888:3111998:312391431239143124393480Streptomyces coelicolor A3(2), complete genomehypothetical protein3e-38157
NC_016109:4455158:446636944663694466818450Kitasatospora setae KM-6054, complete genomehypothetical protein1e-37155
NC_016582:6811273:682279568227956823310516Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein4e-35147
NC_018524:2246225:225237322523732252885513Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomehypothetical protein2e-30131
NC_016887:1093609:110189211018921102413522Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein5e-21100
NC_006361:4098469:410678841067884107303516Nocardia farcinica IFM 10152, complete genomehypothetical protein2e-1892
NC_016887:221788:232330232330232860531Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein6e-1890.1
NC_018524:2246225:225166022516602252202543Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomehypothetical protein8e-1373.2
NC_021177:6127431:613185461318546132600747Streptomyces fulvissimus DSM 40593, complete genomehypothetical protein2e-1272
NC_013510:465188:481615481615482160546Thermomonospora curvata DSM 43183, complete genomehypothetical protein3e-1271.6
NC_016111:5515462:552224355222435522422180Streptomyces cattleya NRRL 8057, complete genomehypothetical protein3e-1064.3
NC_021177:2766910:277926227792622780014753Streptomyces fulvissimus DSM 40593, complete genomehypothetical protein7e-1063.5
NC_010572:5445081:547240554724055472974570Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein2e-0962.4
NC_010572:8493946:854011785401178540650534Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein4e-0961.2
NC_010572:1:528052805813534Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein4e-0961.2
NC_010572:8493946:528052805813534Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein4e-0961.2
NC_014815:4491413:451347945134794514036558Micromonospora sp. L5 chromosome, complete genomehypothetical protein3e-0961.2
NC_016109:7445603:745113474511347451610477Kitasatospora setae KM-6054, complete genomehypothetical protein3e-0858.2
NC_014210:1588426:159876415987641599312549Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,hypothetical protein2e-0652