Pre_GI: BLASTP Hits

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Query: NC_003155:4592000:4622270 Streptomyces avermitilis MA-4680, complete genome

Start: 4622270, End: 4622698, Length: 429

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003155:4906639:491429149142914914755465Streptomyces avermitilis MA-4680, complete genomeregulatory protein8e-58221
NC_013929:5248000:526022052602205260648429Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein3e-56216
NC_016111:2402891:241025224102522410653402Streptomyces cattleya NRRL 8057, complete genomeregulatory protein6e-1992.8
NC_013510:2288746:230050923005092300937429Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase1e-0962
NC_013131:8480384:850365185036518504517867Catenulispora acidiphila DSM 44928, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase1e-0858.5
NC_007333:3244572:325636332563633256776414Thermobifida fusca YX, complete genomehypothetical protein1e-0755.1
NC_013510:5115500:513280551328055133197393Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase2e-0754.7
NC_013510:465188:486773486773487363591Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase2e-0754.3
NC_013510:2432879:244682024468202447224405Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase4e-0650.1
NC_013510:4960500:496857749685774968981405Thermomonospora curvata DSM 43183, complete genomeputative signal transduction histidine kinase8e-0649.3