Pre_GI: BLASTP Hits

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Query: NC_003155:4592000:4602727 Streptomyces avermitilis MA-4680, complete genome

Start: 4602727, End: 4603485, Length: 759

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013008:2851342:285134228513422852088747Escherichia coli O157:H7 str. TW14359 chromosome, complete genomeDNA-binding transcriptional regulator6e-0754.7
NC_017093:2357583:236657423665742367317744Actinoplanes missouriensis 431, complete genomeGntR family transcriptional regulator5e-1994.7
NC_016114:3575955:358320535832053583984780Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeGntR family transcriptional regulator2e-0859.7
NC_015656:5084767:510324051032405103626387Frankia symbiont of Datisca glomerata chromosome, complete genomeGntR family transcriptional regulator1e-0757
NC_017328:2225418:222844922284492229195747Shigella flexneri 2002017 chromosome, complete genomeGntR family transcriptional regulator2e-0653.1
NC_017200:3622838:364600236460023646727726Bacillus thuringiensis serovar finitimus YBT-020 chromosome,GntR family transcriptional regulator4e-0652
NC_016114:3008500:302031030203103021026717Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeGntR family transcriptional regulator1e-1273.9
NC_014318:9604367:962238796223879622740354Amycolatopsis mediterranei U32 chromosome, complete genomeGntR family transcriptional regulator5e-0961.6
NC_016582:5393568:540514154051415405914774Streptomyces bingchenggensis BCW-1 chromosome, complete genomeGntR family transcriptional regulator2e-0756.6
NC_015953:2603526:261081926108192611727909Streptomyces sp. SirexAA-E chromosome, complete genomeGntR family transcriptional regulator1e-1170.5
NC_017186:9604427:962244796224479622800354Amycolatopsis mediterranei S699 chromosome, complete genomeGntR family transcriptional regulator5e-0961.6
NC_015957:1070500:107590210759021076678777Streptomyces violaceusniger Tu 4113 chromosome, complete genomeGntR family transcriptional regulator1e-0757
NC_016822:2341127:234306723430672343813747Shigella sonnei 53G, complete genomeGntR family transcriptional regulator6e-0754.7
NC_011353:2852362:285236228523622853108747Escherichia coli O157:H7 str. EC4115 chromosome, complete genomeGntR family transcriptional regulator6e-0754.7
NC_016582:7101701:711106371110637111593531Streptomyces bingchenggensis BCW-1 chromosome, complete genomeGntR family transcriptional regulator protein6e-0858.2
NC_015656:1469501:148617614861761486967792Frankia symbiont of Datisca glomerata chromosome, complete genomeGntR family transcriptional regulator with UTRA sensor domain4e-0652
NC_015957:639774:646967646967647683717Streptomyces violaceusniger Tu 4113 chromosome, complete genomeGntR family transcriptional regulator with UTRA sensor domain1e-1170.1
NC_003888:4613000:462376646237664624524759Streptomyces coelicolor A3(2), complete genomeGntR-family regulatory protein5e-0651.6
NC_021177:4221309:423668742366874237553867Streptomyces fulvissimus DSM 40593, complete genomeGntR-family transcriptional regulator8e-0650.8
NC_018750:3249756:325719232571923257971780Streptomyces venezuelae ATCC 10712, complete genomeGntR-family transcriptional regulator3e-101368
NC_006677:1255079:126827412682741269014741Gluconobacter oxydans 621H, complete genomeHistidine utilization repressor1e-0653.5
NC_019673:1275627:129120512912051291603399Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein3e-0652.4
NC_003888:3602753:360891636089163609695780Streptomyces coelicolor A3(2), complete genomekorSA, regulatory protein4e-1065.1
NC_021177:4124839:413883841388384139617780Streptomyces fulvissimus DSM 40593, complete genomekorSA, regulatory protein2e-0859.7
CP002185:2347413:235062723506272351373747Escherichia coli W, complete genomepredicted DNA-binding transcriptional regulator6e-0754.7
AC_000091:2185369:218536921853692186115747Escherichia coli W3110 DNA, complete genomepredicted DNA-binding transcriptional regulator6e-0754.7
NC_010473:2267851:227106522710652271811747Escherichia coli str. K-12 substr. DH10B, complete genomepredicted DNA-binding transcriptional regulator6e-0754.7
NC_016113:803268:812013812013812744732Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequenceProtein korA2e-21102
NC_011750:955451:973500973500974246747Escherichia coli IAI39 chromosome, complete genomeputative DNA-binding transcriptional regulator5e-0754.7
NC_011741:2239637:224157722415772242323747Escherichia coli IAI1 chromosome, complete genomeputative DNA-binding transcriptional regulator6e-0754.7
NC_011745:2399313:240125324012532401999747Escherichia coli ED1a chromosome, complete genomeputative DNA-binding transcriptional regulator3e-0755.5
NC_012759:2069326:207254020725402073286747Escherichia coli BW2952 chromosome, complete genomeputative DNA-binding transcriptional regulator6e-0754.7
CU928160:2239637:224157722415772242323747Escherichia coli IAI1 chromosome, complete genomeputative DNA-binding transcriptional regulator6e-0754.7
NC_003198:2179688:220506222050622205808747Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative gntR-family transcriptional regulator5e-0651.6
NC_008278:296526:307974307974308765792Frankia alni ACN14a, complete genomePutative regulatory protein KorSA, GntR-family transcriptional regulator2e-1066.2
NC_018750:4333064:433993843399384340732795Streptomyces venezuelae ATCC 10712, complete genomeputative regulatory protein KorSA, GntR-family transcriptional regulator3e-1065.5
NC_006905:2235607:226199722619972262743747Salmonella enterica subsp. enterica serovar Choleraesuis strputative regulatory protein, gntR family5e-0651.6
NC_007384:2251792:225373222537322254478747Shigella sonnei Ss046, complete genomeputative transcriptional regulator6e-0754.7
NC_002655:2925787:292578729257872926533747Escherichia coli O157:H7 EDL933, complete genomeputative transcriptional regulator6e-0754.7
NC_002695:2854629:285556828555682856314747Escherichia coli O157:H7 str. Sakai, complete genomeputative transcriptional regulator6e-0754.7
NC_008278:1845000:185660018566001857508909Frankia alni ACN14a, complete genomePutative transcriptional regulator (GntR-family)6e-1581.3
NC_013595:151500:158906158906159691786Streptosporangium roseum DSM 43021, complete genomeputative transcriptional regulator, GntR family8e-0857.8
NC_013595:3541012:355596035559603556841882Streptosporangium roseum DSM 43021, complete genomeputative transcriptional regulator, GntR family3e-0652.4
NC_020133:5485528:549970854997085500487780Mycobacterium liflandii 128FXT, complete genomeregulatory protein1e-1377
NC_016947:666627:675648675648676442795Mycobacterium intracellulare MOTT-02 chromosome, complete genomeregulatory protein7e-1374.3
NC_011593:2014787:202250120225012022875375Bifidobacterium longum subsp. infantis ATCC 15697 chromosome,regulatory protein GntR4e-0652
NC_007333:537292:549423549423549740318Thermobifida fusca YX, complete genomeregulatory protein GntR, HTH3e-0652.4
NC_016948:678939:688007688007688786780Mycobacterium intracellulare MOTT-64 chromosome, complete genometranscriptional regulator2e-1272.8
NC_003888:6103534:613628961362896137068780Streptomyces coelicolor A3(2), complete genometranscriptional regulator2e-0963.2
NC_018515:1406816:142889914288991429282384Desulfosporosinus meridiei DSM 13257 chromosome, complete genometranscriptional regulator4e-0755.5
NC_002678:7004370:703210170321017032844744Mesorhizobium loti MAFF303099, complete genometranscriptional regulator4e-0755.5
NC_017219:2014605:202231920223192022693375Bifidobacterium longum subsp. infantis ATCC 15697, complete genometranscriptional regulator4e-0652
NC_013729:2258582:227234522723452272686342Kribbella flavida DSM 17836, complete genometranscriptional regulator, GntR family3e-0755.5
NC_014666:7152782:716610971661097166882774Frankia sp. EuI1c chromosome, complete genometranscriptional regulator, GntR family4e-0652
NC_013235:508585:524691524691525431741Nakamurella multipartita DSM 44233, complete genometranscriptional regulator, GntR family2e-1479.7
NC_013235:682902:696087696087696872786Nakamurella multipartita DSM 44233, complete genometranscriptional regulator, GntR family9e-1167.4
NC_014210:144036:153050153050153823774Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, GntR family5e-1065.1
NC_014815:658893:664402664402665223822Micromonospora sp. L5 chromosome, complete genometranscriptional regulator, gntr family6e-0961.2
NC_011149:2179592:220506922050692205815747Salmonella enterica subsp. enterica serovar Agona str. SL483,transcriptional regulator, GntR family5e-0651.6
NC_016115:62493:637116371164466756Streptomyces flavogriseus ATCC 33331 plasmid pSFLA02, completetranscriptional regulator, GntR family8e-78290
NC_014210:5270643:528191152819115282651741Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,transcriptional regulator, GntR family8e-1374.3
NC_010468:1694729:171221617122161712962747Escherichia coli ATCC 8739, complete genometranscriptional regulator, GntR family6e-0754.7
NC_009921:1611132:161877516187751619167393Frankia sp. EAN1pec, complete genometranscriptional regulator, GntR family1e-0653.9
NC_013093:1411882:141862814186281419329702Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, GntR family7e-0651.2
NC_013729:2157785:217111721711172171860744Kribbella flavida DSM 17836, complete genometranscriptional regulator, GntR family2e-1685.9
NC_013093:1213908:123094312309431231323381Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, GntR family4e-0755.5
NC_007777:5087405:509495850949585095722765Frankia sp. CcI3, complete genometranscriptional regulator, GntR family5e-0651.6