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Query: NC_003155:3095123:3113221 Streptomyces avermitilis MA-4680, complete genome

Start: 3113221, End: 3114744, Length: 1524

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003888:6233478:6241070624107062425961527Streptomyces coelicolor A3(2), complete genomehypothetical protein2e-136486
NC_015957:1968587:1973129197312919746911563Streptomyces violaceusniger Tu 4113 chromosome, complete genomehypothetical protein6e-127454
NC_015953:5777116:5783028578302857844761449Streptomyces sp. SirexAA-E chromosome, complete genomehypothetical protein2e-20100
NC_016111:481115:5388815388815402061326Streptomyces cattleya NRRL 8057, complete genomehypothetical protein6e-2099.4
NC_016582:2554000:2566645256664525681741530Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein6e-1685.9
NC_016114:1710938:1754945175494517565551611Streptomyces flavogriseus ATCC 33331 chromosome, complete genomehypothetical protein1e-1378.6
NC_015656:1618329:1635215163521516366151401Frankia symbiont of Datisca glomerata chromosome, complete genomehypothetical protein4e-1376.6
NC_012490:2067246:2067246206724620687121467Rhodococcus erythropolis PR4, complete genomehypothetical protein1e-1275.1
NC_013510:675368:6812516812516826541404Thermomonospora curvata DSM 43183, complete genomeprotein of unknown function DUF6901e-1274.7
NC_016947:4500329:4518485451848545198581374Mycobacterium intracellulare MOTT-02 chromosome, complete genomehypothetical protein3e-1170.1
NC_009339:201897:2018972018972033571461Mycobacterium gilvum PYR-GCK plasmid pMFLV01, complete sequencehypothetical protein4e-1169.7
NC_013595:8898533:8911747891174789131981452Streptosporangium roseum DSM 43021, complete genomehypothetical protein7e-1168.9
NC_014168:709036:7290547290547305771524Segniliparus rotundus DSM 44985 chromosome, complete genomehypothetical protein5e-0859.7
NC_013093:7722436:7722436772243677240581623Actinosynnema mirum DSM 43827, complete genomeprotein of unknown function DUF6901e-0655.5
NC_013159:403918:4201154201154216741560Saccharomonospora viridis DSM 43017, complete genomeProtein of unknown function (DUF690)2e-0654.3
NC_008726:1533727:1532374153237415337591386Mycobacterium vanbaalenii PYR-1, complete genomeprotein of unknown function DUF6902e-0654.3