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Query: NC_002945:476835:499319 Mycobacterium bovis AF2122/97, complete genome

Start: 499319, End: 500638, Length: 1320

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017186:361444:3614443614443628621419Amycolatopsis mediterranei S699 chromosome, complete genomehypothetical protein3e-30133
NC_016804:477500:4994494994495007681320Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein0756
NC_008769:507000:5291155291155304341320Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein0756
NC_012207:477500:4994484994485007671320Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein0756
NC_015848:483500:5086695086695099881320Mycobacterium canettii CIPT 140010059, complete genomehypothetical protein0756
NC_019950:481881:5046885046885060071320Mycobacterium canettii CIPT 140060008 complete genomeConserved membrane protein of unknown function0756
NC_011896:363448:3843503843503856661317Mycobacterium leprae Br4923, complete genome1e-164580
NC_010612:835648:8616808616808629991320Mycobacterium marinum M, complete genomehypothetical protein0677
NC_009565:479500:5014705014705027891320Mycobacterium tuberculosis F11, complete genomehypothetical protein0756
NC_009525:477093:4996104996105009291320Mycobacterium tuberculosis H37Ra, complete genomeputative conserved membrane protein0752
NC_000962:475816:4983004983004996191320Mycobacterium tuberculosis H37Rv, complete genomePOSSIBLE CONSERVED MEMBRANE PROTEIN0752
NC_012943:476500:4985594985594998781320Mycobacterium tuberculosis KZN 1435 chromosome, complete genomehypothetical protein0756
NC_016768:476500:4985594985594998781320Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein0756