Query: NC_016511:678582 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete
Start: 678582, End: 702302, Length: 23721
Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_014039:708427 | 708427 | 727792 | 19366 | Propionibacterium acnes SK137 chromosome, complete genome | 0 | 38340 | BLASTN svg | BLASTP svg |
NC_014215:2295500 | 2295500 | 2321836 | 26337 | Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, | 4e-30 | 141 | BLASTN svg | BLASTP svg |
NC_009480:739395* | 739395 | 760500 | 21106 | Clavibacter michiganensis subsp. michiganensis NCPPB 382, complete | 5e-23 | 117 | BLASTN svg | BLASTP svg |
NC_015514:3351052* | 3351052 | 3381530 | 30479 | Cellulomonas fimi ATCC 484 chromosome, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_012586:425615 | 425615 | 449129 | 23515 | Rhizobium sp. NGR234 plasmid pNGR234b, complete sequence | 3e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_013093:832971* | 832971 | 856691 | 23721 | Actinosynnema mirum DSM 43827, complete genome | 5e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_008699:1247423* | 1247423 | 1268985 | 21563 | Nocardioides sp. JS614, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_013851:949973* | 949973 | 980519 | 30547 | Allochromatium vinosum DSM 180 chromosome, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_013174:2455420* | 2455420 | 2490806 | 35387 | Jonesia denitrificans DSM 20603, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_012587:713124 | 713124 | 738385 | 25262 | Rhizobium sp. NGR234, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_010170:4409683 | 4409683 | 4435297 | 25615 | Bordetella petrii, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_010125:333895 | 333895 | 356619 | 22725 | Gluconacetobacter diazotrophicus PAl 5, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_006087:2326143 | 2326143 | 2354219 | 28077 | Leifsonia xyli subsp. xyli str. CTCB07, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_002935:2103677 | 2103677 | 2126473 | 22797 | Corynebacterium diphtheriae NCTC 13129, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_014117:442616* | 442616 | 515802 | 73187 | Burkholderia sp. CCGE1002 chromosome chromosome 1, complete | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |