Pre_GI: BLASTN Hits

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Query: NC_009495:3309550 Clostridium botulinum A str. ATCC 3502 chromosome, complete genome

Start: 3309550, End: 3332099, Length: 22550

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well-studied Hall strain that produces type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_012563:3556763*3556763357533918577Clostridium botulinum A2 str. Kyoto, complete genome03435BLASTN svgBLASTP svg
NC_010516:3368951*3368951339250323553Clostridium botulinum B1 str. Okra, complete genome03380BLASTN svgBLASTP svg
NC_014328:3747973*3747973377009922127Clostridium ljungdahlii ATCC 49587 chromosome, complete genome2e-74287BLASTN svgBLASTP svg
NC_010516:514000*51400053623322234Clostridium botulinum B1 str. Okra, complete genome1e-51212BLASTN svgBLASTP svg
NC_010520:496500*49650051930622807Clostridium botulinum A3 str. Loch Maree, complete genome1e-51212BLASTN svgBLASTP svg
NC_012563:519037*51903754582126785Clostridium botulinum A2 str. Kyoto, complete genome1e-51212BLASTN svgBLASTP svg
NC_010520:11460001146000116884922850Clostridium botulinum A3 str. Loch Maree, complete genome3e-49204BLASTN svgBLASTP svg
NC_008262:20256992025699204408118383Clostridium perfringens SM101, complete genome7e-47196BLASTN svgBLASTP svg
NC_003366:21431732143173216513121959Clostridium perfringens str. 13, complete genome1e-45192BLASTN svgBLASTP svg
NC_020291:11498871149887117209922213Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-27131BLASTN svgBLASTP svg
NC_020291:2873000*2873000289187618877Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-27131BLASTN svgBLASTP svg
NC_010674:24171992417199243509917901Clostridium botulinum B str. Eklund 17B, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_016012:879972*87997290262722656Candidatus Arthromitus sp. SFB-rat-Yit, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_008593:980731980731100500724277Clostridium novyi NT, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_003454:63500*6350010726843769Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete1e-0869.9BLASTN svgBLASTP svg
NC_010003:2029416*2029416205389024475Petrotoga mobilis SJ95, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014209:1487699*1487699151184724149Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,7e-0763.9BLASTN svgBLASTP svg
NC_003454:618290*61829063831520026Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete7e-0763.9BLASTN svgBLASTP svg
NC_019978:2071435*2071435209759326159Halobacteroides halobius DSM 5150, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_012563:29254722925472296409938628Clostridium botulinum A2 str. Kyoto, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_010520:28609602860960288097120012Clostridium botulinum A3 str. Loch Maree, complete genome3e-0661.9BLASTN svgBLASTP svg