Query: NC_008262:381323 Clostridium perfringens SM101, complete genome
Start: 381323, End: 404099, Length: 22777
Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_008261:381297 | 381297 | 401887 | 20591 | Clostridium perfringens ATCC 13124, complete genome | 0 | 8288 | BLASTN svg | BLASTP svg |
NC_008262:2598920* | 2598920 | 2649039 | 50120 | Clostridium perfringens SM101, complete genome | 0 | 2256 | BLASTN svg | BLASTP svg |
NC_008262:2649289* | 2649289 | 2704676 | 55388 | Clostridium perfringens SM101, complete genome | 0 | 2236 | BLASTN svg | BLASTP svg |
NC_008262:297960* | 297960 | 323144 | 25185 | Clostridium perfringens SM101, complete genome | 0 | 2196 | BLASTN svg | BLASTP svg |
NC_008262:419726* | 419726 | 440602 | 20877 | Clostridium perfringens SM101, complete genome | 0 | 1411 | BLASTN svg | BLASTP svg |
NC_021182:3576815 | 3576815 | 3600611 | 23797 | Clostridium pasteurianum BC1, complete genome | 1e-69 | 272 | BLASTN svg | BLASTP svg |
NC_014328:303063* | 303063 | 377862 | 74800 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 6e-66 | 260 | BLASTN svg | BLASTP svg |
NC_010674:2435241 | 2435241 | 2459364 | 24124 | Clostridium botulinum B str. Eklund 17B, complete genome | 4e-33 | 151 | BLASTN svg | BLASTP svg |
NC_010723:2231834 | 2231834 | 2254536 | 22703 | Clostridium botulinum E3 str. Alaska E43, complete genome | 4e-33 | 151 | BLASTN svg | BLASTP svg |
NC_010674:1390473 | 1390473 | 1411166 | 20694 | Clostridium botulinum B str. Eklund 17B, complete genome | 1e-26 | 129 | BLASTN svg | BLASTP svg |
NC_007681:657351* | 657351 | 680761 | 23411 | Methanosphaera stadtmanae DSM 3091, complete genome | 5e-26 | 127 | BLASTN svg | BLASTP svg |
NC_014654:549966 | 549966 | 570449 | 20484 | Halanaerobium sp. 'sapolanicus' chromosome, complete genome | 2e-19 | 105 | BLASTN svg | BLASTP svg |
NC_013192:664408* | 664408 | 685917 | 21510 | Leptotrichia buccalis DSM 1135, complete genome | 1e-17 | 99.6 | BLASTN svg | BLASTP svg |
NC_010520:1146000 | 1146000 | 1168849 | 22850 | Clostridium botulinum A3 str. Loch Maree, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_004193:2522000 | 2522000 | 2544345 | 22346 | Oceanobacillus iheyensis HTE831, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_011661:906583* | 906583 | 924599 | 18017 | Dictyoglomus turgidum DSM 6724, complete genome | 7e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_010674:426256* | 426256 | 452294 | 26039 | Clostridium botulinum B str. Eklund 17B, complete genome | 3e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_013515:715009* | 715009 | 751255 | 36247 | Streptobacillus moniliformis DSM 12112, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_019908:323375* | 323375 | 346392 | 23018 | Brachyspira pilosicoli P43/6/78 chromosome, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_014410:615992 | 615992 | 638224 | 22233 | Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome, | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_004722:5057825 | 5057825 | 5085396 | 27572 | Bacillus cereus ATCC 14579, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_007514:1840971* | 1840971 | 1865463 | 24493 | Chlorobium chlorochromatii CaD3, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_012440:1249941 | 1249941 | 1271854 | 21914 | Persephonella marina EX-H1, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015216:1102837 | 1102837 | 1142119 | 39283 | Methanobacterium sp. AL-21 chromosome, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_018604:1137797* | 1137797 | 1160099 | 22303 | Brachyspira pilosicoli WesB complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_011772:5021404* | 5021404 | 5063599 | 42196 | Bacillus cereus G9842, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_018607:1648607* | 1648607 | 1672504 | 23898 | Brachyspira pilosicoli B2904 chromosome, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_008261:576923* | 576923 | 596925 | 20003 | Clostridium perfringens ATCC 13124, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |