Query: NC_005956:152497 Bartonella henselae str. Houston-1, complete genome
Start: 152497, End: 171675, Length: 19179
Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
---|
NC_005955:139907* | 139907 | 157649 | 17743 | Bartonella quintana str. Toulouse, complete genome | 0 | 10200 | BLASTN svg | BLASTP svg |
NC_020300:131782* | 131782 | 150089 | 18308 | Bartonella australis Aust/NH1, complete genome | 0 | 1491 | BLASTN svg | BLASTP svg |
NC_007205:1232734* | 1232734 | 1261048 | 28315 | Candidatus Pelagibacter ubique HTCC1062, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_006831:1112000* | 1112000 | 1136434 | 24435 | Ehrlichia ruminantium str. Gardel, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_007940:97949 | 97949 | 125665 | 27717 | Rickettsia bellii RML369-C, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_009883:1429000 | 1429000 | 1452489 | 23490 | Rickettsia bellii OSU 85-389, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014246:1991093* | 1991093 | 2019860 | 28768 | Mobiluncus curtisii ATCC 43063 chromosome, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015672:203139* | 203139 | 227438 | 24300 | Flexistipes sinusarabici DSM 4947 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014378:525717* | 525717 | 551551 | 25835 | Acetohalobium arabaticum DSM 5501 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_009749:1699152* | 1699152 | 1755952 | 56801 | Francisella tularensis subsp. holarctica FTA, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_008601:1733940* | 1733940 | 1790605 | 56666 | Francisella tularensis subsp. novicida U112, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_008369:1702885* | 1702885 | 1757317 | 54433 | Francisella tularensis subsp. holarctica OSU18, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_007880:1703346* | 1703346 | 1760055 | 56710 | Francisella tularensis subsp. holarctica, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |