Pre_GI: BLASTN Hits

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Query: NC_005956:152497 Bartonella henselae str. Houston-1, complete genome

Start: 152497, End: 171675, Length: 19179

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_005955:139907*13990715764917743Bartonella quintana str. Toulouse, complete genome010200BLASTN svgBLASTP svg
NC_020300:131782*13178215008918308Bartonella australis Aust/NH1, complete genome01491BLASTN svgBLASTP svg
NC_007205:1232734*1232734126104828315Candidatus Pelagibacter ubique HTCC1062, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_006831:1112000*1112000113643424435Ehrlichia ruminantium str. Gardel, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_007940:979499794912566527717Rickettsia bellii RML369-C, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_009883:14290001429000145248923490Rickettsia bellii OSU 85-389, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014246:1991093*1991093201986028768Mobiluncus curtisii ATCC 43063 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_015672:203139*20313922743824300Flexistipes sinusarabici DSM 4947 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014378:525717*52571755155125835Acetohalobium arabaticum DSM 5501 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_009749:1699152*1699152175595256801Francisella tularensis subsp. holarctica FTA, complete genome9e-0660BLASTN svgBLASTP svg
NC_008601:1733940*1733940179060556666Francisella tularensis subsp. novicida U112, complete genome9e-0660BLASTN svgBLASTP svg
NC_008369:1702885*1702885175731754433Francisella tularensis subsp. holarctica OSU18, complete genome9e-0660BLASTN svgBLASTP svg
NC_007880:1703346*1703346176005556710Francisella tularensis subsp. holarctica, complete genome9e-0660BLASTN svgBLASTP svg