Pre_GI: BLASTP Hits

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Query: NC_010516:2064027:2067299 Clostridium botulinum B1 str. Okra, complete genome

Start: 2067299, End: 2067739, Length: 441

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2114222:211749221174922117932441Clostridium botulinum F str. 230613 chromosome, complete genomespermine/spermidine acetyltransferase3e-69259
NC_009699:2116500:211739221173922117832441Clostridium botulinum F str. Langeland chromosome, complete genomespermine/spermidine acetyltransferase3e-69259
NC_010520:2171584:217671421767142177154441Clostridium botulinum A3 str. Loch Maree, complete genomespermine/spermidine acetyltransferase2e-67253
NC_016047:2658000:268411326841132684571459Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completespermine/spermidine acetyltransferase9e-23105
NC_000964:2702376:271757027175702718028459Bacillus subtilis subsp. subtilis str. 168, complete genomespermine/spermidine acetyltransferase2e-22104
NC_014479:2505823:252260425226042523062459Bacillus subtilis subsp. spizizenii str. W23 chromosome, completespermine/spermidine acetyltransferase2e-22104
NC_017195:2498113:252505925250592525517459Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completespermine/spermidine acetyltransferase5e-22103
UCMB5137:1396603:141181014118101412268459Bacillus atrophaeus UCMB-5137spermine/spermidine acetyltransferase4e-22103
NC_019896:1483073:150781515078151508273459Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeSpermine/spermidine acetyltransferase3e-22103
NC_020244:2509000:253298425329842533442459Bacillus subtilis XF-1, complete genomespermine/spermidine acetyltransferase3e-22103
NC_014639:1358597:138214413821441382602459Bacillus atrophaeus 1942 chromosome, complete genomespermine/spermidine acetyltransferase1e-21102
CP002207:1358597:138214413821441382602459Bacillus atrophaeus 1942, complete genomespermine/spermidine acetyltransferase1e-21102
NC_014976:684000:702209702209702667459Bacillus subtilis BSn5 chromosome, complete genomespermine/spermidine acetyltransferase1e-21101
NC_019673:2635585:264389826438982644338441Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein4e-1580.1
NC_009997:4091371:410299041029904103436447Shewanella baltica OS195, complete genomeGCN5-related N-acetyltransferase2e-1374.3
NC_016901:4039335:405095440509544051391438Shewanella baltica OS678 chromosome, complete genomeN-acetyltransferase GCN52e-1374.3
NC_009665:3984080:399669539966953997132438Shewanella baltica OS185 chromosome, complete genomeN-acetyltransferase GCN58e-1372.4
NC_013406:2866000:290625329062532906693441Paenibacillus sp. Y412MC10 chromosome, complete genomeGCN5-like N-acetyltransferase3e-1270.5