Pre_GI: BLASTP Hits

Some Help

Query: NC_009495:1759759:1763282 Clostridium botulinum A str. ATCC 3502 chromosome, complete genome

Start: 1763282, End: 1763854, Length: 573

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well-studied Hall strain that produces type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:33519:556145561456177564Clostridium botulinum F str. 230613 chromosome, complete genomeRNA polymerase sigma-70 factor family1e-32139
NC_009699:33452:554815548156044564Clostridium botulinum F str. Langeland chromosome, complete genomeRNA polymerase factor sigma-701e-32139
NC_009698:38000:603946039460957564Clostridium botulinum A str. Hall chromosome, complete genomeRNA polymerase factor sigma-701e-32139
NC_009697:38000:603936039360956564Clostridium botulinum A str. ATCC 19397 chromosome, completeRNA polymerase factor sigma-701e-32139
NC_009495:38000:605326053261095564Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeRNA polymerase factor sigma-701e-32139
NC_012563:36000:546405464055203564Clostridium botulinum A2 str. Kyoto, complete genomeRNA polymerase sigma-70 factor family2e-32138
NC_012658:35500:543805438054943564Clostridium botulinum Ba4 str. 657 chromosome, complete genomeRNA polymerase factor sigma-709e-32136
NC_010516:42475:604246042460987564Clostridium botulinum B1 str. Okra, complete genomeRNA polymerase sigma-70 factor family1e-31136
NC_010520:35845:544285442854991564Clostridium botulinum A3 str. Loch Maree, complete genomeRNA polymerase sigma-70 factor family3e-31134
NC_015172:1429266:144744914474491448018570Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeRNA polymerase, sigma-24 subunit, ECF subfamily1e-21102
NC_018866:1402259:141560314156031416181579Dehalobacter sp. DCA chromosome, complete genomeRNA polymerase sigma factor1e-0859.7