Pre_GI: BLASTP Hits

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Query: NC_007384:1320287:1325273 Shigella sonnei Ss046, complete genome

Start: 1325273, End: 1326244, Length: 972

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016822:1304398:130811713081171309088972Shigella sonnei 53G, complete genometRNA mo(5)U34 methyltransferase0670
NC_011415:2153243:216932721693272170298972Escherichia coli SE11 chromosome, complete genomehypothetical protein0669
NC_008258:1934479:195271519527151953686972Shigella flexneri 5 str. 8401, complete genomeputative enzyme0668
NC_010465:2383219:238321923832192384190972Yersinia pseudotuberculosis YPIII, complete genomemethyltransferase3e-147521
NC_003143:2309500:232721023272102328181972Yersinia pestis CO92, complete genomehypothetical protein2e-147521
NC_008150:1593500:161152316115231612494972Yersinia pestis Antiqua, complete genomehypothetical protein2e-147521
NC_004088:2491303:249130324913032492274972Yersinia pestis KIM, complete genomeenzyme2e-147521
NC_009381:1205900:120590012059001206871972Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-147521
NC_014029:2285323:228532322853232286294972Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-147521
NC_017160:2212806:221280622128062213777972Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-147521
NC_017168:3433804:343380434338043434775972Yersinia pestis A1122 chromosome, complete genometRNA mo(5)U34 methyltransferase2e-147521
NC_010634:2297000:231407323140732315044972Yersinia pseudotuberculosis PB1/+, complete genomemethyltransferase1e-146519
NC_006155:2378526:239617723961772397148972Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-146519
NC_004547:2810151:282880228288022829785984Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein3e-142504
NC_003910:2175305:219715821971582198126969Colwellia psychrerythraea 34H, complete genomeputative methyltransferase4e-116417
NC_012560:1322000:134496113449611345920960Azotobacter vinelandii DJ, complete genomemethyltransferase7e-95347
NC_021150:1322000:134497313449731345932960Azotobacter vinelandii CA6, complete genomemethyltransferase7e-95347
NC_007645:2294553:231035923103592311333975Hahella chejuensis KCTC 2396, complete genomeSAM-dependent methyltransferase4e-92338
NC_013851:859396:859396859396860373978Allochromatium vinosum DSM 180 chromosome, complete genomemethyltransferase1e-90333
NC_014973:54449:728067280673777972Geobacter sp. M18 chromosome, complete genomemethyltransferase1e-88326
NC_007517:2870657:287375528737552874726972Geobacter metallireducens GS-15, complete genomeMethyltransferase, putative3e-87322