Pre_GI: BLASTP Hits

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Query: NC_006142:811469:813926 Rickettsia typhi str. Wilmington, complete genome

Start: 813926, End: 814159, Length: 234

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017066:811565:814022814022814255234Rickettsia typhi str. TH1527 chromosome, complete genomehypothetical protein2e-36150
NC_017062:812133:814590814590814823234Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein2e-36150
NC_017044:954318:954318954318954551234Rickettsia parkeri str. Portsmouth chromosome, complete genomehypothetical protein2e-29127
NC_016913:232500:256212256212256445234Rickettsia rickettsii str. Brazil chromosome, complete genomehypothetical protein3e-29127
NC_012633:928500:928659928659928892234Rickettsia africae ESF-5, complete genomehypothetical protein7e-28122