Pre_GI: BLASTP Hits

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Query: NC_006085:2384892:2402789 Propionibacterium acnes KPA171202, complete genome

Start: 2402789, End: 2404114, Length: 1326

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014039:2320307:233875623387562339544789Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein5e-153541
NC_016516:2314115:233254723325472333335789Propionibacterium acnes TypeIA2 P.acn33 chromosome, completehypothetical protein6e-153540
NC_017317:1598925:1617294161729416186311338Corynebacterium ulcerans 809 chromosome, complete genomehypothetical protein9e-116417
NC_015673:1038673:1038673103867310400311359Corynebacterium resistens DSM 45100 chromosome, complete genomehypothetical protein7e-114410
NC_012704:947409:9538729538729552091338Corynebacterium kroppenstedtii DSM 44385, complete genomehypothetical protein2e-113409
NC_017303:1454841:1475011147501114763541344Corynebacterium pseudotuberculosis I19 chromosome, complete genomegalactose-1-phosphate uridylyltransferase3e-113409
NC_014039:2320307:233821923382192338734516Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein3e-95348
NC_014246:651801:6522436522436535741332Mobiluncus curtisii ATCC 43063 chromosome, complete genomehypothetical protein7e-95348
NC_016516:2314115:233200923320092332449441Propionibacterium acnes TypeIA2 P.acn33 chromosome, completehypothetical protein2e-80300