Pre_GI: BLASTP Hits

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Query: NC_005957:4169610:4184927 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 4184927, End: 4185271, Length: 345

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011658:4171237:418654641865464186890345Bacillus cereus AH187 chromosome, complete genomehypothetical protein2e-58223
NC_010184:4219257:423221842322184232562345Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein8e-55211
NC_014335:4113154:412745941274594127803345Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein3e-53206
NC_007530:4176462:419577041957704196039270Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein4e-46182
NC_011969:4065460:408190640819064082175270Bacillus cereus Q1 chromosome, complete genomegroup-specific protein6e-43172
NC_011772:4321117:433389743338974334124228Bacillus cereus G9842, complete genomegroup-specific protein2e-34144