Pre_GI: BLASTP Hits

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Query: NC_005956:1648000:1656650 Bartonella henselae str. Houston-1, complete genome

Start: 1656650, End: 1657579, Length: 930

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012846:2004711:2010633201063320117031071Bartonella grahamii as4aup, complete genomephage related protein8e-95347
NC_010161:2155500:2168831216883121698981068Bartonella tribocorum CIP 105476, complete genomehypothetical protein1e-92339
NC_014932:1314881:134203813420381342910873Bartonella clarridgeiae 73, complete genomehypothetical protein2e-53209
NC_008783:177161:1967971967971978131017Bartonella bacilliformis KC583, complete genomehypothetical protein2e-50199
NC_005956:1648000:1657853165785316589981146Bartonella henselae str. Houston-1, complete genomehypothetical protein6e-41168
NC_005956:1648000:165757616575761657869294Bartonella henselae str. Houston-1, complete genomehypothetical protein2e-33142
NC_010577:1188438:121235612123561213243888Xylella fastidiosa M23, complete genomeprotein of unknown function DUF13761e-1274.3
NC_004556:1178897:120281612028161203721906Xylella fastidiosa Temecula1, complete genomehypothetical protein1e-1273.9
NC_008570:2216736:223452922345292235266738Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomehypothetical protein1e-0757.8
NC_009720:4033983:403947340394734040324852Xanthobacter autotrophicus Py2, complete genomehypothetical protein1e-0654.3
NC_010086:810890:824479824479825285807Burkholderia multivorans ATCC 17616 chromosome 2, completehypothetical protein1e-0654.3
NC_010805:1642978:165001916500191650825807Burkholderia multivorans ATCC 17616 chromosome 2, completebacteriophage protein1e-0654.3
NC_010002:2110953:212490021249002125676777Delftia acidovorans SPH-1, complete genomehypothetical protein9e-0651.2