Pre_GI: BLASTP Hits

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Query: NC_004668:2938000:2942159 Enterococcus faecalis V583, complete genome

Start: 2942159, End: 2942707, Length: 549

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017316:2466244:247026524702652470813549Enterococcus faecalis OG1RF chromosome, complete genomeBioY family protein8e-77285
NC_020291:2701149:271249927124992713050552Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein3e-1994.7
NC_019978:224619:239875239875240417543Halobacteroides halobius DSM 5150, complete genomehypothetical protein3e-1167.8
NC_017030:2728175:273955727395572740153597Corallococcus coralloides DSM 2259 chromosome, complete genomeBioY family protein1e-1066.2
NC_003413:1521080:156003915600391560554516Pyrococcus furiosus DSM 3638, complete genomehypothetical protein8e-1063.5
NC_014408:1193239:119823511982351198897663Methanothermobacter marburgensis str. Marburg chromosome, completebiotin biosynthesis protein1e-0962.4
NC_017955:1506221:152346815234681524031564Modestobacter marinus, complete genomeABC transporter2e-0962
NC_010080:1885677:189328418932841893826543Lactobacillus helveticus DPC 4571, complete genomehypothetical protein4e-0961.2
NC_018528:1932000:194199319419931942535543Lactobacillus helveticus R0052 chromosome, complete genomehypothetical protein5e-0960.5
NC_015172:775128:780241780241780801561Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeBioY protein4e-0857.8
NC_015320:211147:216733216733217359627Archaeoglobus veneficus SNP6 chromosome, complete genomeBioY protein9e-0856.6
NC_021182:162236:164845164845165411567Clostridium pasteurianum BC1, complete genomehypothetical protein2e-0755.1
NC_014335:4622500:462684146268414627434594Bacillus cereus biovar anthracis str. CI chromosome, completebiotin synthesis BioY protein3e-0754.7
NC_005945:4670978:467670546767054677298594Bacillus anthracis str. Sterne, complete genomebioY family protein3e-0754.7
NC_007530:4674335:467560846756084676201594Bacillus anthracis str. 'Ames Ancestor', complete genomebioy family protein3e-0754.7
NC_003997:4674209:467548246754824676075594Bacillus anthracis str. Ames, complete genomebioY family protein3e-0754.7
NC_012659:4674235:467550846755084676101594Bacillus anthracis str. A0248, complete genomebioY family protein3e-0754.7
NC_009718:643200:678566678566679090525Fervidobacterium nodosum Rt17-B1, complete genomeBioY protein3e-0754.7
NC_005957:4680089:468088346808834681476594Bacillus thuringiensis serovar konkukian str. 97-27, completebiotin synthesis BioY protein3e-0754.7
NC_016779:4645155:464948946494894650082594Bacillus cereus F837/76 chromosome, complete genomeECF transporter substrate-specific protein BioY3e-0754.7
NC_012472:4691251:469558546955854696178594Bacillus cereus 03BB102, complete genomebioY family protein3e-0754.7
NC_008600:4687500:469186646918664692459594Bacillus thuringiensis str. Al Hakam, complete genomebiotin synthesis protein3e-0754.7
NC_006274:4742489:474682247468224747415594Bacillus cereus E33L, complete genomebiotin synthesis BioY protein3e-0754.7
NC_011773:4732457:473679147367914737384594Bacillus cereus AH820 chromosome, complete genomebioY family protein3e-0754.7
NC_016629:3629848:363140536314053631950546Desulfovibrio africanus str. Walvis Bay chromosome, completeBioY protein4e-0754.3
NC_000961:135493:138195138195138683489Pyrococcus horikoshii OT3, complete genomehypothetical protein5e-0754.3
NC_017200:4697500:470136047013604701953594Bacillus thuringiensis serovar finitimus YBT-020 chromosome,bioY family protein6e-0753.9
NC_014171:4740500:474345347434534744046594Bacillus thuringiensis BMB171 chromosome, complete genomeBioY protein9e-0753.1
NC_015602:1949610:196026219602621960603342Lactobacillus kefiranofaciens ZW3 chromosome, complete genomeBioY family protein8e-0753.1
NC_010830:193379:210897210897211469573Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein1e-0652.8
NC_011969:4613430:461776746177674618360594Bacillus cereus Q1 chromosome, complete genomebioy family protein1e-0652.4
NC_011658:4672000:467635646763564676949594Bacillus cereus AH187 chromosome, complete genomebioY family protein1e-0652.4
NC_014210:618500:621954621954622586633Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,BioY protein3e-0651.6
NC_014643:2056280:211902121190212119614594Rothia dentocariosa ATCC 17931 chromosome, complete genomeBioY family protein3e-0651.6
NC_015913:1248000:125277712527771253310534Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomehypothetical protein5e-0650.8
NC_010337:2339056:233905623390562339592537Heliobacterium modesticaldum Ice1, complete genomebiotin synthesis BioY protein5e-0650.8
NC_004722:4824818:482758048275804828101522Bacillus cereus ATCC 14579, complete genomeBioY protein9e-0649.7