Pre_GI: BLASTP Hits

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Query: NC_004557:2777291:4027 Clostridium tetani E88, complete genome

Start: 4027, End: 4548, Length: 522

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004557:1:402740274548522Clostridium tetani E88, complete genomeDNA polymerase, bacteriophage-type7e-99358
NC_014328:85290:107289107289107885597Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative uracil DNA glycosylase3e-61233
NC_012658:35500:475754757548171597Clostridium botulinum Ba4 str. 657 chromosome, complete genomeuracil-DNA glycosylase family protein7e-60229
NC_010520:35845:477384773848334597Clostridium botulinum A3 str. Loch Maree, complete genomeuracil-DNA glycosylase family protein4e-59227
NC_012563:36000:479634796348559597Clostridium botulinum A2 str. Kyoto, complete genomeuracil-DNA glycosylase family protein1e-58225
NC_010516:42475:536985369854294597Clostridium botulinum B1 str. Okra, complete genomeuracil-DNA glycosylase family protein3e-58224
NC_009495:38000:536215362154217597Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeuracil-DNA glycosylase1e-58224
NC_009697:38000:536365363654232597Clostridium botulinum A str. ATCC 19397 chromosome, completeuracil-DNA glycosylase1e-58224
NC_009698:38000:536365363654232597Clostridium botulinum A str. Hall chromosome, complete genomeuracil-DNA glycosylase1e-58224
NC_009699:33452:488894888949485597Clostridium botulinum F str. Langeland chromosome, complete genomeuracil-DNA glycosylase1e-58224
NC_017297:33519:489584895849554597Clostridium botulinum F str. 230613 chromosome, complete genomeuracil-DNA glycosylase family protein1e-58224
NC_015425:2690448:271486127148612715559699Clostridium botulinum BKT015925 chromosome, complete genomeUracil DNA glycosylase superfamily protein3e-58223
NC_021182:93000:123127123127123723597Clostridium pasteurianum BC1, complete genomeuracil-DNA glycosylase6e-58223
NC_008593:2457594:248069624806962481367672Clostridium novyi NT, complete genomeUracil DNA glycosylase superfamily protein1e-57222
NC_009706:3845039:385801738580173858613597Clostridium kluyveri DSM 555 chromosome, complete genomeUracil DNA glycosylase-like protein1e-56218
NC_011837:3776541:378951937895193790115597Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-56218
NC_009012:3653111:366431736643173664895579Clostridium thermocellum ATCC 27405, complete genomeUracil-DNA glycosylase superfamily3e-32137
NC_011898:2907017:291642629164262917082657Clostridium cellulolyticum H10, complete genomeUracil-DNA glycosylase superfamily1e-28125
NC_016627:3815690:382968038296803830276597Clostridium clariflavum DSM 19732 chromosome, complete genomeuracil-DNA glycosylase, family 42e-27121
NC_007530:1459412:146339514633951464036642Bacillus anthracis str. 'Ames Ancestor', complete genomeuracil-dna glycosylase family protein6e-22103
NC_005945:1459357:146334914633491463990642Bacillus anthracis str. Sterne, complete genomeuracil-DNA glycosylase family protein6e-22103
NC_010610:1765000:176509117650911765753663Lactobacillus fermentum IFO 3956, complete genomehypothetical protein3e-21101
NC_019978:875941:880801880801881439639Halobacteroides halobius DSM 5150, complete genomeuracil-DNA glycosylase, family 43e-1994.4
NC_010718:497222:513312513312513899588Natranaerobius thermophilus JW/NM-WN-LF, complete genomephage SPO1 DNA polymerase-related protein7e-1993.2
NC_000868:643548:646000646000646590591Pyrococcus abyssi GE5, complete genomehypothetical protein3e-1890.9
NC_011297:1224749:122849612284961229128633Dictyoglomus thermophilum H-6-12, complete genomeDNA polymerase, bacteriophage-type3e-1787.8
NC_015555:49842:785997859979162564Thermoanaerobacterium xylanolyticum LX-11 chromosome, completephage SPO1 DNA polymerase-related protein9e-1786.3
NC_015865:1468689:149674714967471497334588Thermococcus sp. 4557 chromosome, complete genomeUracil-DNA glycosylase1e-1686.3
NC_000961:1303446:131809213180921318685594Pyrococcus horikoshii OT3, complete genomehypothetical protein1e-1685.9
NC_012785:205502:228731228731229354624Kosmotoga olearia TBF 19.5.1, complete genomephage SPO1 DNA polymerase-related protein3e-1684.3
NC_012440:373863:383921383921384571651Persephonella marina EX-H1, complete genomeuracil-DNA glycosylase family 4 protein4e-1684
NC_019970:35985:648766487665433558Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeuracil-DNA glycosylase, family 44e-1684
NC_015318:219484:221339221339221968630Hippea maritima DSM 10411 chromosome, complete genomephage SPO1 DNA polymerase-like protein5e-1684
NC_009253:3317533:333294833329483333511564Desulfotomaculum reducens MI-1 chromosome, complete genomephage SPO1 DNA polymerase-like protein5e-1684
NC_014410:51711:782997829978856558Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,phage SPO1 DNA polymerase-related protein1e-1582.4
NC_010320:1769486:178335617833561783916561Thermoanaerobacter sp. X514 chromosome, complete genomephage SPO1 DNA polymerase-like protein1e-1582.4
NC_014538:73272:813248132481884561Thermoanaerobacter sp. X513 chromosome, complete genomephage SPO1 DNA polymerase-related protein1e-1582.4
NC_015958:84270:974389743897998561Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomephage SPO1 DNA polymerase-like protein2e-1582
NC_005213:295994:323644323644324240597Nanoarchaeum equitans Kin4-M, complete genomehypothetical protein2e-1581.6
NC_005213:202400:323644323644324240597Nanoarchaeum equitans Kin4-M, complete genomehypothetical protein2e-1581.6
NC_016148:1105669:110940111094011110021621Thermovirga lienii DSM 17291 chromosome, complete genomephage SPO1 DNA polymerase-related protein2e-1581.6
NC_007355:2237630:226111122611112261656546Methanosarcina barkeri str. fusaro chromosome 1, complete sequenceDNA polymerase4e-1580.9
NC_013939:1417750:143969114396911440314624Deferribacter desulfuricans SSM1, complete genomeuracil-DNA glycosylase4e-1580.9
NC_020419:782337:800253800253801014762Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, completeuracil-DNA glycosylase1e-1479.3
NS_000191:782337:800253800253801014762Uncultured Termite group 1 bacterium phylotype Rs-D17, completeuracil-DNA glycosylase1e-1479.3
NC_012658:99899:101380101380101952573Clostridium botulinum Ba4 str. 657 chromosome, complete genomeuracil-DNA glycosylase1e-1479
NC_015416:1103900:112360311236031124181579Methanosaeta concilii GP-6 chromosome, complete genomeuracil DNA glycosylase2e-1478.6
NC_005213:202400:30893830893838041471477Nanoarchaeum equitans Kin4-M, complete genometRNA-Trp3e-1478.2
NC_005213:295994:30893830893838041471477Nanoarchaeum equitans Kin4-M, complete genometRNA-Trp3e-1478.2
NC_019940:3660754:368095436809543681742789Thioflavicoccus mobilis 8321 chromosome, complete genomeuracil-DNA glycosylase, family 42e-1478.2
NC_017954:1:229422942935642Thermogladius cellulolyticus 1633 chromosome, complete genomephage SPO1 DNA polymerase-related protein5e-1477.4
NC_018876:2563725:257042925704292571016588Methanolobus psychrophilus R15 chromosome, complete genomeuracil-DNA glycosylase5e-1477
NC_013216:4131563:414455541445554145130576Desulfotomaculum acetoxidans DSM 771, complete genomephage SPO1 DNA polymerase-related protein2e-1375.1
NC_008686:405159:407573407573408388816Paracoccus denitrificans PD1222 chromosome 1, complete sequencephage SPO1 DNA polymerase-related protein3e-1374.7
NC_005070:1144777:116441111644111164974564Synechococcus sp. WH 8102, complete genomeUracil-DNA glycosylase3e-1374.7
NC_010003:1444623:145579314557931456473681Petrotoga mobilis SJ95, complete genomephage SPO1 DNA polymerase-related protein4e-1374.3
NC_016627:3815690:383025538302553830824570Clostridium clariflavum DSM 19732 chromosome, complete genomeuracil-DNA glycosylase, family 45e-1373.9
NC_014718:630188:636366636366637190825Burkholderia rhizoxinica HKI 454 chromosome, complete genomeUracil DNA glycosylase superfamily protein5e-1373.6
NC_000854:278711:300613300613301296684Aeropyrum pernix K1, complete genomeuracil-DNA glycosylase7e-1373.2
NC_009012:3653111:366376936637693664338570Clostridium thermocellum ATCC 27405, complete genomephage SPO1 DNA polymerase-related protein2e-1272
NC_010793:721944:738292738292739098807Orientia tsutsugamushi str. Ikeda, complete genomebacteriophage-type DNA polymerase2e-1272
NC_002967:2507993:251479525147952515589795Treponema denticola ATCC 35405, complete genomeDNA polymerase domain protein4e-1270.9
NC_015381:2859000:2860589286058928620701482Burkholderia gladioli BSR3 chromosome 1, complete sequencephage SPO1 DNA polymerase-related protein9e-1269.7
NC_011027:1971580:200840320084032009026624Chlorobaculum parvum NCIB 8327, complete genomephage SPO1 DNA polymerase-related protein1e-1168.9
NC_009668:1726000:172971417297141730337624Ochrobactrum anthropi ATCC 49188 chromosome 2, complete sequencephage SPO1 DNA polymerase-related protein3e-1167.8
NC_011898:2907017:291708429170842917656573Clostridium cellulolyticum H10, complete genomephage SPO1 DNA polymerase-related protein4e-1167.4
NC_014831:285759:3066593066593076601002Thermaerobacter marianensis DSM 12885 chromosome, complete genomephage SPO1 DNA polymerase-related protein5e-1167.4
NC_004842:1081271:110217411021741103046873Anaplasma marginale str. St. Maries, complete genomehypothetical protein6e-1167
NC_005071:835005:852991852991853614624Prochlorococcus marinus str. MIT 9313, complete genomeUracil-DNA glycosylase4e-1064.3
NC_007513:1126914:114702511470251147588564Synechococcus sp. CC9902, complete genomePhage SPO1 DNA polymerase-related protein6e-1063.5
NC_011761:2546081:256280025628002563726927Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completeuracil-DNA glycosylase7e-1063.2
NC_011206:2447905:246462424646242465550927Acidithiobacillus ferrooxidans ATCC 53993, complete genomephage SPO1 DNA polymerase-related protein7e-1063.2
NC_019908:1512622:152161415216141522414801Brachyspira pilosicoli P43/6/78 chromosome, complete genomeuracil DNA glycosylase3e-0961.6
NC_007777:75885:940209402094670651Frankia sp. CcI3, complete genomephage SPO1 DNA polymerase-related protein1e-0859.3
NC_008343:1699132:1717869171786917193351467Granulibacter bethesdensis CGDNIH1, complete genomeuracil DNA glycosylase superfamily protein2e-0858.5
NC_014722:1552454:1553662155366215552331572Burkholderia rhizoxinica HKI 454, complete genomeuracil DNA glycosylase superfamily protein5e-0857.4
NC_014166:1077121:109583610958361096504669Arcobacter nitrofigilis DSM 7299 chromosome, complete genomeuracil-DNA glycosylase superfamily4e-0650.8