Pre_GI: BLASTP Hits

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Query: NC_004557:2777291:2785527 Clostridium tetani E88, complete genome

Start: 2785527, End: 2786114, Length: 588

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014393:4988127:500945250094525010039588Clostridium cellulovorans 743B chromosome, complete genomeRubrerythrin2e-79295
NC_018870:757416:785148785148785741594Thermacetogenium phaeum DSM 12270 chromosome, complete genomerubrerythrin4e-72270
NC_020134:2832857:283767628376762838272597Clostridium stercorarium subsp. stercorarium DSM 8532, completerubrerythrin-16e-67253
NC_014314:1148000:117315811731581173736579Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completerubrerythrin7e-62236
NC_015164:2626503:262650326265032627081579Bacteroides salanitronis DSM 18170 chromosome, complete genomeRubrerythrin1e-59228
NC_014836:1180454:119410111941011194694594Desulfurispirillum indicum S5 chromosome, complete genomeRubrerythrin3e-58224
NC_007519:1244198:124784012478401248415576Desulfovibrio alaskensis G20 chromosome, complete genomerubrerythrin2e-57221
NC_013173:3890370:390876239087623909340579Desulfomicrobium baculatum DSM 4028, complete genomeRubrerythrin2e-56218
NC_008011:860000:875739875739876314576Lawsonia intracellularis PHE/MN1-00, complete genomeRubrerythrin4e-56217
NC_015519:1113095:112785211278521128388537Tepidanaerobacter sp. Re1 chromosome, complete genomeRubrerythrin2e-55214
NC_019903:421000:422523422523423107585Desulfitobacterium dichloroeliminans LMG P-21439 chromosome,rubrerythrin2e-54211
NC_018867:2354000:237389623738962374432537Dehalobacter sp. CF chromosome, complete genomeRubrerythrin2e-52204
NC_015500:1204501:120990912099091210448540Treponema brennaborense DSM 12168 chromosome, complete genomeRubrerythrin4e-52204
NC_010337:98974:106366106366106929564Heliobacterium modesticaldum Ice1, complete genomerubrerythrin3e-51201
NC_009464:1397739:139962413996241400208585Uncultured methanogenic archaeon RC-I, complete genomerubrerythrin3e-51201
NC_010001:649000:664806664806665345540Clostridium phytofermentans ISDg, complete genomeRubrerythrin1e-50199
NC_015562:1460124:148837114883711488940570Methanotorris igneus Kol 5 chromosome, complete genomeRubrerythrin4e-49194
NC_018604:2377549:239965823996582400194537Brachyspira pilosicoli WesB complete genomerubrerythrin7e-49193
NC_014624:3538094:355354735535473554086540Eubacterium limosum KIST612 chromosome, complete genomerubrerythrin3e-48191
NC_015311:2235550:225452422545242255177654Prevotella denticola F0289 chromosome, complete genomerubredoxin1e-47189
NC_014371:1328500:132968613296861330339654Prevotella melaninogenica ATCC 25845 chromosome chromosome II,rubredoxin1e-47189
NC_014376:2921769:2941089294108929422791191Clostridium saccharolyticum WM1 chromosome, complete genomeRubrerythrin2e-47188
NC_015320:893686:914342914342914914573Archaeoglobus veneficus SNP6 chromosome, complete genomeRubrerythrin3e-47187
NC_015636:1635400:164514716451471645734588Methanothermococcus okinawensis IH1 chromosome, complete genomeRubrerythrin7e-47186
NC_013887:1402980:141003014100301410629600Methanocaldococcus sp. FS406-22 chromosome, complete genomeRubrerythrin2e-46185
NC_000909:657904:665918665918666532615Methanocaldococcus jannaschii DSM 2661, complete genomerubrerythrin (rr)1e-45182
NC_013156:980888:989278989278989862585Methanocaldococcus fervens AG86, complete genomeRubrerythrin4e-45180
NC_015977:2280834:228259022825902283132543Roseburia hominis A2-183 chromosome, complete genomeRubrerythrin5e-44177
NC_014152:421481:450069450069450599531Thermincola sp. JR, complete genomeRubrerythrin5e-38157
NC_017294:403422:417944417944418498555Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomerubrerythrin3e-37154
NC_015320:893686:913773913773914318546Archaeoglobus veneficus SNP6 chromosome, complete genomeRubrerythrin2e-36151
NC_012039:53497:686026860269249648Campylobacter lari RM2100, complete genomerubrerythrin4e-34144
NC_009802:1977596:199409619940961994740645Campylobacter concisus 13826, complete genomeenolase (2-phosphoglycerate dehydratase; 2-phospho-D-glycerate hydro-lyase)1e-31135
NC_017192:1137724:113772411377241138383660Arcobacter sp. L, complete genomerubrerythrin3e-28124
NC_014330:888366:892557892557893069513Brachyspira pilosicoli 95/1000 chromosome, complete genomerubrerythrin4e-25114
NC_017243:3093393:309963330996333100130498Brachyspira intermedia PWS/A chromosome, complete genomerubrerythrin6e-25113
NC_018607:2231975:223621722362172236714498Brachyspira pilosicoli B2904 chromosome, complete genomerubrerythrin9e-25113
NC_019908:2312194:232736123273612327858498Brachyspira pilosicoli P43/6/78 chromosome, complete genomerubrerythrin9e-25113
NC_018604:2350054:235429723542972354794498Brachyspira pilosicoli WesB complete genomerubrerythrin9e-25113
NC_012225:2247796:226070422607042261201498Brachyspira hyodysenteriae WA1, complete genomerubrerythrin7e-24110
NC_002754:2391867:240413324041332404567435Sulfolobus solfataricus P2, complete genomeRubrerythrin (rr)6e-21100
NC_012632:2564801:257184925718492572283435Sulfolobus islandicus M.16.27 chromosome, complete genomerubrerythrin4e-2097.4
NC_012589:2605085:261045126104512610885435Sulfolobus islandicus L.S.2.15, complete genomeRubrerythrin6e-2097.1
NC_012588:2483000:248775624877562488190435Sulfolobus islandicus M.14.25 chromosome, complete genomerubrerythrin6e-2097.1
NC_012622:2571812:257926225792622579696435Sulfolobus islandicus Y.G.57.14 chromosome, complete genomerubrerythrin6e-2097.1
NC_012623:2680601:268596626859662686400435Sulfolobus islandicus Y.N.15.51 chromosome, complete genomerubrerythrin6e-2097.1
NC_012726:2461102:246815024681502468584435Sulfolobus islandicus M.16.4 chromosome, complete genomerubrerythrin6e-2097.1
NC_013769:2591065:259643125964312596865435Sulfolobus islandicus L.D.8.5 chromosome, complete genomerubrerythrin6e-2097.1
NC_017275:2519637:252668525266852527119435Sulfolobus islandicus HVE10/4 chromosome, complete genomerubrerythrin6e-2097.1
NC_017276:2391645:239869323986932399127435Sulfolobus islandicus REY15A chromosome, complete genomerubrerythrin6e-2097.1
NC_010718:2513917:252461925246192525167549Natranaerobius thermophilus JW/NM-WN-LF, complete genomeRubrerythrin8e-2096.7
NC_014972:3771642:379050237905023791002501Desulfobulbus propionicus DSM 2032 chromosome, complete genomeRubrerythrin2e-1995.5
NC_018870:2316499:236637523663752367355981Thermacetogenium phaeum DSM 12270 chromosome, complete genomenigerythrin2e-1892
NC_009922:2487492:250524725052472505876630Alkaliphilus oremlandii OhILAs, complete genomeRubrerythrin1e-1686.7
NC_008609:2840249:285281528528152853321507Pelobacter propionicus DSM 2379, complete genomeRubrerythrin4e-1684.7
NC_007955:1108000:112675711267571127248492Methanococcoides burtonii DSM 6242, complete genomeRubrerythrin5e-1684.3
NC_015318:1151422:117048411704841170990507Hippea maritima DSM 10411 chromosome, complete genomeRubrerythrin1e-1582.8
NC_015474:1490668:149066814906681491183516Pyrococcus sp. NA2 chromosome, complete genomerubrerythrin4e-1374.3
NC_019942:112182:120200120200120706507Aciduliprofundum sp. MAR08-339, complete genomerubrerythrin1e-1272.8
NC_012881:2957309:297357729735772974074498Desulfovibrio salexigens DSM 2638, complete genomeRubrerythrin6e-1270.9
NC_010001:3369500:338451633845163384896381Clostridium phytofermentans ISDg, complete genomeRubrerythrin7e-1270.5
NC_014720:2420455:242291924229192423473555Caldicellulosiruptor kronotskyensis 2002 chromosome, completerubrerythrin8e-1270.1
NC_012883:1695703:170246417024641702979516Thermococcus sibiricus MM 739, complete genomeRubrerythrin1e-1169.3
NC_014844:3582677:358267735826773583174498Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomeRubrerythrin1e-1169.3
NC_013926:829665:838800838800839306507Aciduliprofundum boonei T469 chromosome, complete genomeRubrerythrin2e-1168.6
NC_018604:1045774:106705110670511067590540Brachyspira pilosicoli WesB complete genomerubrerythrin3e-1168.6
NC_014330:2268773:228998422899842290571588Brachyspira pilosicoli 95/1000 chromosome, complete genomerubrerythrin3e-1168.6
NC_015680:841783:860225860225860740516Pyrococcus yayanosii CH1 chromosome, complete genomerubrerythrin4e-1167.8
NC_014328:2872721:287272128727212873275555Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative rubrerythrin9e-1166.6